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Table 3 Optimal cut-off values for cytokines, with sensitivity, specificity and positive and negative predictive values

From: Interleukin 6, lipopolysaccharide-binding protein and interleukin 10 in the prediction of risk and etiologic patterns in patients with community-acquired pneumonia: results from the German competence network CAPNETZ

 

Cut-off value

Sensitivity

Specificity

PPV

NPV

Interleukin-6

27.2 pg/ml

70.5

60.4

0.057

0.984

Interleukin-10

3.15 pg/ml

67.3

58.1

0.051

0.981

LBP

22.45 μg/ml

55.2

66.6

0.053

0.978

  1. Positive predictive values (PPV) and negative predictive values (NPV) were obtained using Bayes' formula, with a prevalence of 0.0326. LBP, lipopolysaccharide-binding protein.