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Table 3 Optimal cut-off values for cytokines, with sensitivity, specificity and positive and negative predictive values

From: Interleukin 6, lipopolysaccharide-binding protein and interleukin 10 in the prediction of risk and etiologic patterns in patients with community-acquired pneumonia: results from the German competence network CAPNETZ

  Cut-off value Sensitivity Specificity PPV NPV
Interleukin-6 27.2 pg/ml 70.5 60.4 0.057 0.984
Interleukin-10 3.15 pg/ml 67.3 58.1 0.051 0.981
LBP 22.45 μg/ml 55.2 66.6 0.053 0.978
  1. Positive predictive values (PPV) and negative predictive values (NPV) were obtained using Bayes' formula, with a prevalence of 0.0326. LBP, lipopolysaccharide-binding protein.