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Table 5 Comparisons of patients with mMRC = 0 and patients with mMRC ≥ 1 concerning clinical characteristics, lung function and biological parameters

From: The modified Medical Research Council scale for the assessment of dyspnea in daily living in obesity: a pilot study

  MRC = 0 (n = 7) MRC ≥ 1 (n = 38)
Demographic characteristics   
 Age 50 ± 10 51 ± 11
 Sex (M/F) 4/3 13/25
BMI (kg/m 2 ) 36 ± 5 44 ± 9*
Smoking history   
 Pack-years 10 ± 16 10 ± 17
PFTs   
 FEV1,% pred 101 ± 16 86 ± 17*
 VC,% pred 103 ± 15 90 ± 20
 FEV1/VC 0.78 ± 0.05 0.77 ± 0.11
 FRC,% pred 100 ± 16 91 ± 25
 ERV,% pred 91 ± 32 50 ± 31**
 TLC,% pred 101 ± 11 97 ± 17
 DLCO,% pred 86 ± 18 83 ± 19
Arterial blood gases   
 PaO2 (mmHg) 99 ± 24 88 ± 14
 PaCO2 (mmHg) 39 ± 4 39 ± 4
6-minute walk test   
 6-minute walk distance (m) 524 ± 72 401 ± 107**
 SpO2 at rest (%) 98 ± 2 97 ± 2
 SpO2 after exertion (%) 94 ± 2 96 ± 2
 Borg score at res 0.1 ± 0.4 1.1 ± 1.6
 Borg score after 6MWT 3.9 ± 3 5.7 ± 2.1
Biological parameters   
 Hemoglobin (g/dL) 14.8 ± 1,3 13.7 ± 1,5*
 NT pro-BNP (pg/mL) 97 ± 199 121 ± 301
 CRP (mg/L) 5 ± 4,9 9.1 ± 7,4
 Triglyceride (mmol/L) 1.9 ± 0,9 1.5 ± 0,8
 Total cholesterol (mmol/L) 5.4 ± 1 4.7 ± 1
 Fasting glucose (mmol/L) 5.3 ± 0,8 7.8 ± 3,3
 Hba1c (%) 5.7 ± 0,6 6.8 ± 1,6
  1. Data are expressed as number (%) or mean ± SD; *p value < 0.05, **p value < 0.01.
  2. FEV1: expiratory volume in one second, pred: predicted value, VC: vital capacity, FRC: functional residual capacity, ERV: expiratory reserve volume, TLC: total lung capacity, DLCO: carbon monoxide diffusing capacity of the lung, NT pro-BNP: N-terminal pro brain natriuretic peptide, CRP: serum C reactive protein, HbA1c: glycated hemoglobin.
  3. Normal biological parameters values were based on the normal values for our laboratory: fasting glucose: 3.3 to 6.1 mmol/L; HbA1c: 4 to 6%; total cholesterol: 3 to 5.2 mmol/L; triglycerides: 0.3 to 1.7 mmol/L; NT-pro BNP < 300 pg/mL; CRP < 10 mg/L. Anemia was defined as hemoglobin level < 13 g/dL in men and 12 g/dL in women.