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Table 2 Inspiratory effort for varying levels of pressure support for C = 0.02 L/cm H 2 O, k =6.6, V t =700 ml, and RR = 25 bpm

From: Bench experiments comparing simulated inspiratory effort when breathing helium-oxygen mixtures to that during positive pressure support with air

 

Ventilator Work [J/I]

Gas

Psupport [cm H20]

Inspiratory Effort [J/I]

Theoretical

Experimental*

Medical Air

0

3.52 ± 0.25

  

10

2.66 ± 0.11

1.00

0.86 ± 0.36

15

2.08 ± 0.03

1.50

1.44 ± 0.28

He/O278/22

0

2.45 ± 0.01

  

10

1.77 ± 0.20

1.00

0.68 ± 0.21

15

1.15 ± 0.01

1.50

1.30 ± 0.02

  1. *Determined from the difference between inspiratory effort at Psupport = 0 and that at Psupport = 10 or 15 cm H2O.