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Table 1 GINA recommended treatment steps for 5 to 18 year olds

From: A systematic review with attempted network meta-analysis of asthma therapy recommended for five to eighteen year olds in GINA steps three and four

Step 1

Step 2

Step 3 (Select one)

Step 4 (Add one or more)

SABA

Low dose ICS

A. Medium-or high dose ICS

A. Medium-or high dose ICS + LABA

  

B. Low dose ICS + LABA

B. LTRA

  

C. Low dose ICS + LTRA

C. Theophylline

  

D. Low dose ICS + Theophylline

 
  1. SABA = rapidly acting ß2-agonists; ICS = Inhaled Corticosteroids; LABA = Long–acting β2-adrenoceptor agonists; LTRA = Leukotriene modifier.