Figure 3
A – Mean change in FEV 1 (L): mean change from baseline to pre-dose at weeks 2, 4, 8, and 12, Full Analysis Set (LOCF). * P-value ≤ 0.05 versus fluticasone/formoterol 100/10 μg b.i.d. combination therapy treatment group. Baseline means were 2.416 L, 2.425 L, 2.459 L, and 2.352 L for the fluticasone/formoterol, fluticasone, formoterol, and placebo treatment groups, respectively, for all patients in the Full Analysis Set. b.i.d. = twice daily; FEV1 = forced expiratory volume in the first second; LOCF = last observation carried forward. Figure 3 B – Mean change in FEV 1 (L): mean change from baseline to 2 hours post-dose at weeks 2, 4, 8, and 12, Full Analysis Set (LOCF) . * P-value ≤ 0.05 versus fluticasone/formoterol 100/10 μg b.i.d. combination therapy treatment group. Baseline means were 2.416 L, 2.425 L, 2.459 L, and 2.352 L for the fluticasone/formoterol, fluticasone, formoterol, and placebo treatment groups, respectively, for all patients in the Full Analysis Set. b.i.d. = twice daily; FEV1 = forced expiratory volume in the first second; LOCF = last observation carried forward.