Figure 2From: A novel model-based approach for dose determination of glycopyrronium bromide in COPD Dose−response results of FEV 1 AUC 0-24h at steady-state (modified intent-to-treat population). Model average placebo-adjusted values for OD and BID dosing regimens, with 90% confidence limits (red and blue shaded areas, respectively). FEV1: forced expiratory volume in one second; AUC: area under the curve; OD: once daily; BID: twice daily.Back to article page