From: Prevalence of obstructive sleep apnea in Asian adults: a systematic review of the literature
Study | Country | Study design | Population studied | OSA/SDB prevalence | Risk factors and associated states | Quality assessment score |
---|---|---|---|---|---|---|
Ip et al. [20]; 2001 | China/Hong-Kong | Cross-Sectional study using sleep questionnaire and PSG | n-784 (153 underwent PSG) Males-100% Mean age-41.2 years Mean BMI-23.9 kg/m2 | 23% had snoring. 41.8% were diagnosed with OSA by PSG. Estimated OSA and OSAS prevalence was 8.8% and 4.1% | Older age, higher BMI, snoring and time taken to fall asleep | 6 points: single area study, no funding information. |
Ip et al. [21]; 2004 | China/Hong-Kong | Cross-Sectional study using sleep questionnaire and PSG | n-884 (105 underwent PSG) Females-100% Mean age-41.6 years Mean BMI-22.4 kg/m2 | 15% had snoring. AHI ≥ 5, AHI ≥ 10 and AHI ≥ 15 were present among 30%, 15% and 10% respectively. Estimated prevalence of OSA and OSAS was 3.7% and 2.1% respectively | Older age and higher BMI | 5 points: single area study, no discussion of potential limitations and no funding information. |
Hui et al. [22]; 2006 | China/Hong-Kong | Cross-Sectional study using sleep questionnaire, 4 channel home sleep monitoring and PSG | n-1,477 (211 undergone 4 channel home sleep study and 25 have been assessed by PSG) Males-65.74% Mean age-45.3 years Mean BMI- 24.9 kg/m2 | EDS was present in 60.9%, falling asleep in 24%, snoring in 23.9% and witnessed apnea in 3.7%. RDI ≥ 5 was present in 83.9% and RDI ≥ 15 was present in 17.5%. It was estimated that OSA and OSAS was present in 8.4% and 4.4% respectively | Higher BMI, neck circumference and snoring | 6 points: single area study, no funding information. |
He et al. [23]; 2010 | China | Cross-Sectional study using PSG | n-2,297 Males-86.24% Mean age-46 years Mean BMI- 27.64 kg/m2 | 88.81% were diagnosed with OSA and 51.28% were diagnosed with severe OSA | Systolic and diastolic blood pressure | 6 points: no discussion of the potential limitations and no funding information. |
Chen et al. [24]; 2011 | China | Cross-Sectional study using PSG | n-1,035 Males-83.67% Mean age-45 years Mean BMI- 26.2 kg/m2 in mild OSAS, 27.5 kg/m2 for moderate and 28.8 kg/m2 for severe OSAS | 75.9% had OSAS and 37.7% had AHI > 40. | ESS score correlated with ODI, AHI and BMI. ODI was associated with ESS score. | 6 points: Single area study and no discussion of the potential limitations. |
Tanigawa et al. [25]; 2004 | Japan | Cross-Sectional study using pulse oximetry monitoring | n-1,424 Males-100% mean age-58.6 years Mean BMI-24 kg/m2 | 31.46% and 9% had ODI of 5–15 and ODI > 15 respectively | Arterial hypertension, BMI, smoking and older age | 4 points: single area study, PSG was not used, no discussion of the potential limitations and no funding information. |
Cui et al. [26]; 2006 | Japan | Cross-Sectional study using pulse oximetry monitoring | n-1,313 Males-96% Mean age- for 3% ODI of 5–14 was 47 years and 47.3 years for 3% ODI > 15Mean BMI- 3% ODI of 5–14 was 25.6 kg/m2 and 28.5 kg/m2 for 3% ODI > 15 | Subjects aged 40–69 have SDB prevalence of 8.5% compared to 4% among aged 20-39 | age ≥ 40 years, higher BMI, ESS > 11 and arterial hypertension | 6 points: PSG was not used, no funding information. |
Okabayashi et al. [27]; 2007 | Japan | Cross-Sectional study using home pulse oximetry and then PSG study among Japanese workers | n-368 underwent home pulse oximetry and 153 were screened with PSG Males-100% Mean age-45.7 years Mean BMI-25.8 kg/m2 | 313 patients out of 368 (85%) had ODI ≥ 5 events. 149 out of 153 (97.3%) had OSA | 7 points: no funding information. | |
Asaoka et al. [28]; 2010 | Japan | Cross-Sectional study using 3 channel home sleep monitoring in patients with positive ESS and/or snoring, witnessed apneas, BMI ≥ 25 kg/m2 and concomitant arterial hypertension | n-370 undergone home sleep study; 129 participants undergone PSG study Males-100% Mean age-44.5 years Mean BMI-24.3 kg/m2 | OSA was present among 3.7% | 5 points: single area study, PSG was not used, no funding information | |
Sharma et al. [29]; 2006 | India | Cross-Sectional study using sleep questionnaire and PSG | n-2,150 Males-52.8% Mean age-43.9 years for snorers Mean BMI- 27 kg/m2 151 subjects (77 snorers and 74 nonsnorers) undergone PSG | 25.16% subjects were found to have OSA and 7.28% subjects were found to have OSAS (among who underwent PSG). It was estimated that 13.74% and 3.57% of the population should have OSA and OSAS respectively | Male gender, older age, snoring, higher BMI and greater waist to hip ratio | 6 points: single area study, no funding information. |
Reddy et al. [30]; 2009 | India | Cross-Sectional study using sleep questionnaire and PSG | n-2,505 Males-50.4% Mean age-41 years Mean BMI-24.3 kg/m2 360 subjects (287 snorers and 73 nonsnorers) undergone PSG | 26.94% subjects had OSA and 12.2% subjects had OSAS (among who underwent PSG). | Male gender, BMI ≥ 25 kg/m2 and abdominal obesity | 7 points: single area strudy. |
Kim et al. [31]; 2004 | Korea | Cross-Sectional study using home sleep study or PSG | n- 457 Males- 67.6% Mean age-49.1 years for males with snoring and 54.3 years for females with snoring Mean BMI-26.5 kg/m2 for males with snoring and 26.6 kg/m2 for females with snoring | OSA and was found in 42% men and 20% women and OSAS was present in 4.5% men and 3.2% women | Male gender, higher BMI and hypertension | 7 points: single area study. |
Yusoff et al. [32]; 2010 | Malaysia | Cross-Sectional study using PSG | n-279 Males-100% Mean age-43.8 years Mean BMI- 29.4 kg/m2 for patients with OSA | 44.3% had AHI ≥ 5 and 6.6% had xAHI ≥ 30. | Older age, greater BMI and neck circumference, snoring and hypertension | 7 points: no discussion of the potential limitations. |
Puvanendran et al. [33]; 1999 | Singapore | Cross-Sectional study using PSG | n-106 male: female ratio 9:1 No data on mean age and mean BMI are provided | 87.5% had OSA and 72% had OSAS. It was calculated that 15.7% of the Singaporean population may have OSA. | 6 points: no discussion of the potential limitations and no funding information. |