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Table 2 Demographic characteristics according to the inflammatory phenotype

From: Distribution of sputum cellular phenotype in a large asthma cohort: predicting factors for eosinophilic vs neutrophilic inflammation

 

Paucigranulocytic phenotype

Eosinophilic phenotype

Neutrophilic phenotype

Mixed granulocytic phenotype

N.

203 (40%)

211 (41.5%)

80 (15.7%)

14 (2.8%)

Sex (M/F)

72/131

101/110*

21/59

7/7

Age, yrs

51 (21–86)

51 (19–87)

57 (21–84)

68 (31–88)

Atopy (Y/N)

100/103 (49%)

140/71 (66%)*

48/32 (60%)

8/6 (57%)

Smoking (Y/N)

48/155 (23%)

38/173 (18%)

12/68 (15%)

3/11 (21%)

ICS therapy

    

-Steroid naïve

66 (32.5%)

59 (28%)

25 (31.3%)

3 (21.4%)

-Low dose

31 (15.3%)

37 (17.5%)

4 (5%)*

1 (7.2%)

-Moderate dose

58 (28.6%)

54 (25.6%)

23 (28.7%)

3 (21.4%)

-High dose

48 (23.6%)

61 (28.9%)

28 (35%)

7 (50%)

  1. *p < 0.05, **p < 0.001, ***p < 0.0001 *Paucigranulocytic asthma is used as the comparator.
  2. ICS: inhaled corticosteroids. Low dose: ≤500 μg/day beclomethasone; Moderate dose: 500-1000 μg/day beclomethasone; High dose: >1000 μg/day beclomethasone.