Table 1 Characteristics of the study population at baseline and after 1 month of CPAP
From: Effects of CPAP on nitrate and norepinephrine levels in severe and mild-moderate sleep apnea
Mild/moderate OSA patients (n = 36) | Severe OSA patients (n = 31) | |||
|---|---|---|---|---|
Baseline | Post CPAP | Baseline | Post CPAP | |
Age (yrs) | 48 ± 10.4 | NA | 51 ± 6.3 | NA |
Body mass index (Kg/m2) | 29 ± 3.8* | 30 ± 3.8 | 35 ± 5.1* | 35 ± 5.0 |
Epworth score | 11 ± 6.2# | 3.1 ± 2.5 | 12 ± 6.3 # | 4.2 ± 3.2 |
RDI (n/h) | 16 ± 6.8* | # 3 ± 2.5 | 66 ± 24.2# | 4 ± 2.3 |
Mean SaO2 (%) | 95 ± 1.3* | # 96 ± 1.2 | 91 ± 4.8# | 95 ± 1.2 |
Minimum SaO2 (%) | 86 ± 4.8* | # 93 ± 2.1 | 71 ± 9.9# | 93 ± 2.2 |
SaO2 < 90% (% of TST) | 1 ± 3.2* | # 0 ± 0.2 | 27 ± 26.6# | 0 ± 0.1 |
ODI (n/h) | 10 ± 9.5* | # 0 ± 0.2 | 52 ± 20.5# | 0 ± 0.2 |
Arousal index (n/h) | 23 ± 8.1* | # 16 ± 9.2 | 53 ± 18# | 14 ± 7 |
Compliance (h/night) | NA | 6.3 ± 1.3 | NA | 6.6 ± 0.9 |
95th percentile CPAP pressure (cmH2O) | NA | 11.5 ± 1.8 | NA | 13.2 ± 1.5 |
24h MAP (mmHg) | 91 ± 6.8* | 92 ± 6.9 | 97 ± 8.1# | 92 ± 9 |
Daytime BP (mmHg) | ||||
Systolic | 127 ± 8.3* | 127 ± 8.8 | 134 ± 10.9# | 130 ± 10.1 |
Diastolic | 81 ± 6.2* | 70 ± 7.5 | 85 ± 5.8 # | 80 ± 6.2 |
Nighttime BP (mmHg) | ||||
Systolic | 114 ± 7.9* | 116 ± 10.3 | 125 ± 14.2# | 119 ± 12.9 |
Diastolic | 70 ± 7.6* | 70 ± 7.5 | 76 ± 9.3# | 73 ± 8.9 |
Nox 11pm (μm) | 34.3 ± 21.8+ | 41.3 ± 22.2 | 34.5 ± 21.9 & | 41.4 ± 19.8 |
Nox 4am (μm) | 29.4 ± 15.4+ | 37.7 ± 21.1 | 27.2 ± 14.4 & | 37.4 ± 17.9 |
Nox 7am (μm) | 26.4 ± 14.1+ | 36.6 ± 19.5 | 24.3 ± 16.8 & | 35.2 ± 16.7 |
ΔNOX (%) | 16.5 ± 18.5+ | 9.3 ± 16.3 | 27.6 ± 20.1 & | 0.79 ± 52.2 |
U-NE (μg/24h) | 48.5 ± 19.9* | 47 ± 21.3 | 73.9 ± 30.1# | 55.4 ± 21.8 |