Skip to main content

Table 1 Characteristics of the study population at baseline and after 1 month of CPAP

From: Effects of CPAP on nitrate and norepinephrine levels in severe and mild-moderate sleep apnea

  Mild/moderate OSA patients (n = 36) Severe OSA patients (n = 31)
  Baseline Post CPAP Baseline Post CPAP
Age (yrs) 48 ± 10.4 NA 51 ± 6.3 NA
Body mass index (Kg/m2) 29 ± 3.8* 30 ± 3.8 35 ± 5.1* 35 ± 5.0
Epworth score 11 ± 6.2# 3.1 ± 2.5 12 ± 6.3 # 4.2 ± 3.2
RDI (n/h) 16 ± 6.8* # 3 ± 2.5 66 ± 24.2# 4 ± 2.3
Mean SaO2 (%) 95 ± 1.3* # 96 ± 1.2 91 ± 4.8# 95 ± 1.2
Minimum SaO2 (%) 86 ± 4.8* # 93 ± 2.1 71 ± 9.9# 93 ± 2.2
SaO2 < 90% (% of TST) 1 ± 3.2* # 0 ± 0.2 27 ± 26.6# 0 ± 0.1
ODI (n/h) 10 ± 9.5* # 0 ± 0.2 52 ± 20.5# 0 ± 0.2
Arousal index (n/h) 23 ± 8.1* # 16 ± 9.2 53 ± 18# 14 ± 7
Compliance (h/night) NA 6.3 ± 1.3 NA 6.6 ± 0.9
95th percentile CPAP pressure (cmH2O) NA 11.5 ± 1.8 NA 13.2 ± 1.5
24h MAP (mmHg) 91 ± 6.8* 92 ± 6.9 97 ± 8.1# 92 ± 9
Daytime BP (mmHg)     
Systolic 127 ± 8.3* 127 ± 8.8 134 ± 10.9# 130 ± 10.1
Diastolic 81 ± 6.2* 70 ± 7.5 85 ± 5.8 # 80 ± 6.2
Nighttime BP (mmHg)     
Systolic 114 ± 7.9* 116 ± 10.3 125 ± 14.2# 119 ± 12.9
Diastolic 70 ± 7.6* 70 ± 7.5 76 ± 9.3# 73 ± 8.9
Nox 11pm (μm) 34.3 ± 21.8+ 41.3 ± 22.2 34.5 ± 21.9 & 41.4 ± 19.8
Nox 4am (μm) 29.4 ± 15.4+ 37.7 ± 21.1 27.2 ± 14.4 & 37.4 ± 17.9
Nox 7am (μm) 26.4 ± 14.1+ 36.6 ± 19.5 24.3 ± 16.8 & 35.2 ± 16.7
ΔNOX (%) 16.5 ± 18.5+ 9.3 ± 16.3 27.6 ± 20.1 & 0.79 ± 52.2
U-NE (μg/24h) 48.5 ± 19.9* 47 ± 21.3 73.9 ± 30.1# 55.4 ± 21.8
  1. Values shown as mean ± SD. RDI, respiratory disturbance index; SaO2, arterial oxygen saturation; TST, total sleep time; ODI, oxygen desaturation index; MAP, mean arterial pressure; BP, blood pressure; NOX, nitrate levels; ΔNOX, percentage decrease in NOx during the night; U-NE, urinary norepinephrine; NA, Not applicable.
  2. *: p < 0.05 comparison of baseline values between patients with severe and mild-moderate OSA (unpaired t-test).
  3. #: p < 0.05 comparison between pre- and post-CPAP values (paired t-test).
  4. + p < 0.05 comparison between different time points and between pre- and post-CPAP for patients with mild-moderate OSA (multivariate ANOVA analysis).
  5. & p < 0.05 comparison between different time points and between pre- and post-CPAP for patients with severe OSA (multivariate ANOVA analysis).