Table 2 Biochemical, lung function, and QOL value before and after in the three groups
| Â | Control group (Ctrl) | CPT treatment | HFCWO treatment | Difference between after and before | |||||
|---|---|---|---|---|---|---|---|---|---|
| Â | difference | difference | difference | CPT | HFCWO | HFCWO | |||
| Â | After-before | After-before | After-before | vs Ctrl | vs Ctrl | vs CPT | |||
| Â | Mean | SD | Mean | SD | Mean | SD | P-value (covariance analysis) | ||
WC (103 cell) | 957.0 | 915.7 | 407.0 | 2211.2 | −673.8 | 1093.6 | 0.42 | 0.02 | 0.123 |
RC (106 cell) | −82.0 | 62.3 | 26.0 | 164.7 | 73.0 | 202.5 | 0.13 | 0.03 | 0.503 |
Neutr % | 5.4 | 9.2 | 1.2 | 4.2 | −4.0 | 8.5 | 0.23 | 0.01 | 0.136 |
Lymph % | −1.4 | 3.7 | −1.4 | 2.8 | 0.6 | 7.2 | 0.99 | 0.37 | 0.377 |
FVC (ml) | −37.0 | 35.0 | 54.5 | 153.7 | 192.1 | 80.9 | 0.06 | 0.001 | 0.006 |
FEV1 (ml) | −21.0 | 30.7 | −94.0 | 128.3 | 135.5 | 93.4 | 0.09 | 0.001 | 0.001 |
Tiff.Ind. | −0.6 | 1.3 | −0.6 | 3.5 | 3.1 | 6.7 | 0.99 | 0.07 | 0.072 |
TLC (ml) | 46.0 | 95.6 | −88.0 | 312.4 | −657.0 | 1088.9 | 0.65 | 0.02 | 0.063 |
RV (ml) | 65.0 | 58.5 | −145.0 | 327.8 | −580.0 | 1118.1 | 0.49 | 0.04 | 0.160 |
Mip (cmH2O) | −4.1 | 2.5 | 2.1 | 13.2 | 9.8 | 10.1 | 0.16 | 0.003 | 0.088 |
Mep (cmH2O) | −8.3 | 3.9 | 2.4 | 23.6 | 6.5 | 7.2 | 0.10 | 0.03 | 0.530 |
paO2 (mmHg) | −1.4 | 3.5 | 0.8 | 9.5 | 1.7 | 8.8 | 0.54 | 0.38 | 0.786 |
paCO2 (mmHg) | 0.9 | 1.8 | 1.1 | 2.5 | −0.9 | 2.7 | 0.82 | 0.10 | 0.066 |
ph | −0.004 | 0.010 | 0.001 | 0.023 | 0.016 | 0.028 | 0.59 | 0.049 | 0.143 |
BCSS | 3.1 | 1.4 | 0.2 | 1.8 | −2.7 | 1.8 | 0.001 | 0.001 | 0.001 |
MMRC | 1.0 | 0.8 | −0.5 | 1.1 | −0.7 | 0.8 | 0.001 | 0.001 | 0.629 |
CAT | 9.9 | 3.6 | 0.4 | 6.8 | −8.0 | 4.0 | 0.001 | 0.001 | 0.001 |
C-R Prot. | 1.3 | 1.1 | 0.0 | 0.9 | −1.0 | 0.8 | 0.01 | 0.001 | 0.019 |