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Table 5 Pulmonary and vagal function tests of asthmatics (categorized according to reflux (on pH monitoring) and GERD symptom score following distal esophageal acid or saline perfusion

From: Response of the airways and autonomic nervous system to acid perfusion of the esophagus in patients with asthma: a laboratory study

  Asthmatics with reflux and a negative GERD symptom score( n= 10) Asthmatics with reflux and a positive GERD symptom score( n= 10) Asthmatics without reflux and a negative GERD symptom score( n= 10) Asthmatics without reflux and a positive GERD symptom score (n=10)
  Saline Acid Saline Acid Saline Acid Saline Acid
FVC (L) 3.0 ± 0.2 3.0 ± 0.2 3.0 ± 0.2 3.0 ± 0.2 3.4 ± 0.2 3.3 ± 0.2 3.1 ± 0.1 3.1 ± 0.1
FEV1 (L) 2.6 ± 0.2 2.4 ± 0.1 2.6 ± 0.2 2.4 ± 0.2 2.8 ± 0.2 2.8 ± 0.1 2.6 ± 0.1 2.6 ± 0.1
PEFR (L/min) 4.1 ± 0.2 4.1 ± 0.2 4.2 ± 0.2 4.1 ± 0.2 4.1 ± 0.3 3.9 ± 0.2 3.8 ± 0.2 3.7 ± 0.2
HR Ratio 1.1 ± 0.02 1.1 ± 0.03 1.1 ± 0.02 1.1 ± 0.03 1.2 ± 0.06 1.2 ± 0.05 1.0 ± 0.02 1.0 ± 0.03
HR diff 23.7 ± 2.3 26.0 ± 2.8 23.7 ± 2.4 26.0 ± 2.8 22.0 ± 2.6 25.2 ± 3.2 24.8 ± 2.8 27.0 ± 3.1
VR 1.2 ± 0.06 1.4 ± 0.1 1.2 ± 0.06 1.4 ± 0.09 1.2 ± 0.1 1.3 ± 0.1 1.3 ± 0.05 1.4 ± 0.09
  1. All values as mean ± SE.
  2. FVC Forced Vital Capacity, FEV 1 Forced Expiratory Volume in 1st second, PEFR Peak Expiratory Flow Rate.
  3. HR Ratio Heart rate ratio (30th beat/ 15th beat) on standing from supine position, HR Diff Heart rate difference between inspiration and expiration during deep breathing at 6 cycles per minute, VR ratio of maximum heart rate during the valsalva maneuver to the maximum heart rate around the 20th beat after stopping the maneuver.