Figure 2

With incremental exercise, cardiopulmonary parameters at peak exercise before and after 3-week administration of ghrelin or placebo with PR. Solid symbols, ghrelin; Open symbols, placebo. Data are presented as means ± SD. * p < 0.05, ** p < 0.01: change between pre-treatment and post-treatment (between ghrelin and placebo group difference, treatment effect) by unpaired t-test: ^† p < 0.05, ^†† p < 0.01: repeated-measures ANOVA indicates significant time-course effects of ghrelin versus placebo. $\stackrel{•}{V}{o}_2$, oxygen uptake; V_D/V_T, physiologic dead space/tidal volume ratio, $\stackrel{•}{V}E$, minute ventilation; V_T, tidal volume.