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Table 5 Results of effects of DM programs

From: The health economic impact of disease management programs for COPD: a systematic literature review and meta-analysis

 

Biomedical, physiological health outcomes and exacerbations

Health related quality of life

Relative Risk of mortality

[36]

RD

RD

 

• Fev1% predicted= -0.02

• SGRQ= -0.03

• Fev1 reversibility= -0.27

• VAS= 0.03*

• Tiffeneau index= 0.02

[31]

RR

SMD

• 1.01(0.30-3.37)

• Hospitalization= 0.78 (0.69-0.89)

• SGRQ=-0.15*

• VAS= 1.01

• Exacerbations= 1.39 (1.10-1.74)

• EQ-5D= 0.17

SMD

• MRC= 0.58*

• 6MWD= 0.30

• Endurance time=0.37*

• Handgrip force= 0.24

• PI max= 0.29

• BMI= -1.22

• Fev1% predicted= -0.13

[37]

SMD

SMD

 

• 6MWD= 0.99*

• SGRQ= 0.01

• Peak work rate=-0.88

• VAS=-0.07

• Peak Vo2= -0.06

• Energy= -0.30*

• Pain= 0.20

• Emotional reaction= -0.90*

• Sleep= 3.62

• Isolation= -0.40

• Physical mobility=0.18

• Voorrips total= 1.27*

[39]

RR

  

• Hospitalization= 0.35 (0.29-0.43)

• ED visits= 0.39 (0.33-0.45)

[28]

RR

  

• Days in hosp= 0.28 (0.24-0.32)

• Absenteeism from work= 0.05 (0.03-0.09)

[38]#

RR

SMD

• 0.55 (0.19-1.58)

• Hospitalization= 0.54(0.48-

• SGRQ= -0.29*

 

• 0.61)*

• Hospitalization 1 or more= 0.64(0.45-.91)*

• ED visits=0.64 (0.53-0.78)*

• ED visit 1 or more= 0.64(0.48-0.86)*

SMD

• Fev1=0.00

• FVC=0.00

[29]#

SMD

SMD

• 0.95 (0.20-4.63)

• 6MWD= -0.09

• SGRQ= -0.03

 

[30]#

RR

 

• 0.50 (0.20-1.25)

• Hospitalization= 1.20 (1.04-1.38)

due to COPD=0.13 (0.02-0.97)*

• Hospitalization 1 or more= 1.08 (0.74-1.57)

• Exacerbation 1 or more= 1.00 (0.87-1.15)

[34]#

RR

 

• 0.75 (0.50-1.13)

• Hospitalization= 0.72 (0.65-0.79)*

• ED visits=0.73 (0.68-0.79)*

[32]#

RR

 

• 0.33 (0.04-2.87)

• Hospitalization= 1.72 (1.02-2.90)

• Hospitalization 1 or more = 1.08 (0.75-1.57)

[33]#

RD

RD

 

• Hospitalization=-0.53

• SGRQ=-0.04

• ED visits=-0.66

• ICU admission=-0.57

• Absenteeism from work= -0.77

  1. * Significant (p<0.05) - SGRQ St. George's respiratory questionnaire, VAS Visual analogue scale, FEV1%pred % predicted forced expiratory volume in 1 second, FEV1 Rev Forced expiratory volume in 1 second reversibility, MRC Medical research council dyspnoea scale, 6MWD= Six-minute walk distance, EQ-5D EuroQoL 5 dimensions, PImax Maximal inspiratory mouth pressure, Peak VO2 Peak oxygen uptake mL-1 kg-1 min-1, BMI Body mass index, ED visits Emergency department visits, FVC Forced vital capacity, Days in hosp= Days in hospital, ICU admission Intensive care unit admission.