VT10 ml/kg (n = 74) | VT6 ml/kg (n = 76) | P–value | |
---|---|---|---|
Age (years) | 58 (± 17) | 63 (± 15) | 0.06 |
Male sex | 50 (68%) | 49 (64%) | 0.69 |
APACHE II–score | 20 (± 8) | 21 (± 7) | 0.93 |
SOFA score | 8 (± 4) | 7 (± 3) | 0.19 |
LIS | 1.2 (± 0.6) | 1.3 (± 0.6) | 0.08 |
P/F | 40.0 (± 18.9) | 36.0 (± 11.4) | 0.14 |
Fluid balance before randomization (liters) | 2.2 (± 2.7) | 1.8 (± 1.7) | 0.28 |
Presence of brain injury | 29 (39%) | 21 (28%) | 0.13 |
Presence of heart failure | 22 (30%) | 35 (46%) | 0.04 |
Presence of kidney injury | 31 (42%) | 32 (42%) | 0.97 |
Risk | 17 (23%) | 14 (18%) | |
Injury | 8 (11%) | 13 (17%) | |
Failure | 6 (8%) | 5 (7%) |