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Figure 2 | BMC Pulmonary Medicine

Figure 2

From: Bone marrow-derived progenitor cells in end-stage lung disease patients

Figure 2

Differential progenitor cell profiles in end-stage lung disease patients. (A) Percentage of bone marrow cells (BMCs) positive for CCSP in each disease group (n = 26 donor, n = 5 Bronchiolitis Obliterans (BO), n = 27 Cystic Fibrosis (CF), n = 34 Chronic Obstructive Pulmonary Disease (COPD), n = 41 Pulmonary Fibrosis (PF), n = 11 Pulmonary Hypertension (PH)). (B) Percentage of peripheral blood mononuclear cells (PBMCs) positive for CCSP in each disease group. (n = 29 donor, n = 6 BO, n = 33 CF, n = 41 COPD, n = 53 PF, n = 13 PH). (C) Percentage of peripheral blood leukocytes (PBLs) positive for CD45 and collagen-1 in each disease group (n = 17 donor, n = 6 BO, n = 14 CF, n = 22 COPD, n = 26 PF, n = 8 PH). (D) Ratio of CCSP+ PBMCs to CD45+collagen-1+ fibrocytes in each disease group, compared to lung donors (n = 13 donor, n = 6 BO, n = 10 CF, n = 17 COPD, n = 18 PF, n = 8 PH). Kruskal-Wallis test with Dunn’s multiple comparison post-hoc analysis. Boxes show the median, 25th and 75th percentiles. Whiskers represent the 2.5 and 97.5 percentiles.

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