Figure 6
From: Bone marrow-derived progenitor cells in end-stage lung disease patients
In vitro migration assay. Migration of freshly isolated peripheral blood mononuclear cells (PBMCs) or bone marrow cells (BMCs) in response to chemotactic stimuli Regulated upon Activation, Normal T-cell Expressed, and Secreted (RANTES) (n = 9 control, 11 recipient PBMC, 7 BMC), Interferon gamma-induced protein 10 (IP-10) (n = 9 control, 11 recipient PBMC, 7 BMC), Stromal Derived Factor-1 (SDF-1) (n = 9 control, 13 recipient PBMC, 9 BMC), or Stem Cell Growth Factor-beta (SCGF-β) (n = 4 control, 4 recipient PBMC, 4 BMC), compared to untreated cells. Migrated cells were analyzed for CCSP+ expression and normalized to total CCSP+ cells in the starting sample. Kruskal-Wallis test with Dunn’s multiple comparison post-hoc analysis, with significance tested against untreated samples (* = p < 0.05, ** = p < .01). Boxes show the median, 25th and 75th percentiles. Whiskers represent the 2.5 and 97.5 percentiles.