Table 4 Adjusted estimates of GSTM2 diplotypes on GSTM2 CpG site methylation by secondhand smoke exposure status at age 18
|  | cg03942855†| cg06970744†| ||||||
|---|---|---|---|---|---|---|---|---|
| Â | Not exposed (n = 93) | Exposed (n = 130) | Not exposed (n = 93) | Exposed (n = 130) | ||||
Diplotype* | β (%) | p-value§ | β (%) | p-value§ | β (%) | p-value§ | β (%) | p-value§ |
TC_AC | -2.09 | 0.31 | -1.61 | 0.33 | -0.53 | 0.80 | -2.16 | 0.34 |
TC_TC | 1.62 | 0.31 | -1.80 | 0.03 | 2.19 | 0.42 | -2.75 | 0.02 |
TG_AC | -1.92 | 0.33 | -4.12 | 0.002 | 2.64 | 0.51 | -3.14 | 0.07 |
TG_TG | -1.99 | 0.31 | -1.99 | 0.02 | -2.38 | 0.42 | -3.28 | 0.01 |
Minor diplotypes | -3.88 | 0.33 | 2.26 | 0.50 | -4.04 | 0.57 | 3.23 | 0.48 |
TC_TG | REF | -- | REF | -- | REF | -- | REF | -- |
pinteraction‡ | 0.03 | 0.01 | ||||||