Table 2 Association between the amount of smoke exposure, as reflected by the number of cigarettes smoked daily and number of packyears and clinical and inflammatory variables at baseline
From: Inflammation and corticosteroid responsiveness in ex-, current- and never-smoking asthmatics
Cigarettes/day | Packyears | |||
|---|---|---|---|---|
b | p-value | b | p-value | |
FEV1 (L) | 0.13 | 0.508 | –0.01 | 0.450 |
FEV1 (%predicted) | 0.06 | 0.897 | –0.31 | 0.034 |
Reversibility (%predicted) | –0.22 | 0.162 | –0.00 | 0.968 |
PC20 methacholine (doubling concentrations) | 0.11 | 0.050 | 0.04 | 0.123 |
PC20 AMP (doubling concentrations) | 0.19 | 0.031 | 0.02 | 0.593 |
Sputum eosinophils (%)* | –0.06 | 0.024 | –0.01 | 0.496 |
Blood eosinophils (109/L)* | –0.02 | 0.021 | 0.00 | 0.645 |
Sputum ECP (μg/L)* | –0.04 | 0.313 | –0.00 | 0.839 |
Serum ECP (μg/L)* | –0.04 | 0.025 | 0.00 | 0.829 |
Sputum neutrophils (%)* | –0.00 | 0.779 | 0.00 | 0.713 |
Blood neutrophils (109/L)* | 0.00 | 0.673 | –0.00 | 0.338 |
Exhaled NO (ppb) | –0.09 | 0.708 | 0.10 | 0.254 |