Exhaled nitric oxide is related to atopy, but not asthma in adolescents with bronchiolitis in infancy

BMC Pulmonary Medicine

Table 1 Characteristics of 108 children hospitalized for bronchiolitis in their first year of life during 1997–98 at the university hospitals of Stavanger and Bergen (Norway) according to asthma and atopy at 11 years of age

	Healthy (n = 64)	Atopic non-asthmatic (n = 20)	P-value	Current non-atopic asthma (n = 15)	P-value	Current atopic asthma (n = 9)	P-value
Boys, n (% of group)	30 (47)	14 (70)	0.080	10 (67)	0.252	6 (67)	0.308
Age at hospitalization^* (months)	3.5 (2.0, 6.0)	4.0 (1.0, 10.0)	0.603	6.0 (3.0, 9.0)	0.052	5.0 (4.0, 9.5)	0.083
Age at follow up^* (year)	11.4 (11.0, 11.8)	11.3 (10.9, 11.5)	0.182	11.4 (10.9, 11.6)	0.745	11.6 (11.3, 12.2)	0.410
Weight at follow-up^† (kg)	41.2 (9.3)	40.6 (8.2)	0.791	42.8 (7.5)	0.525	42.5 (8.3)	0.692
Height at follow-up^† (cm)	149.0 (8.2)	147.2 (4.3)	0.206	149.3 (5.6)	0.888	148.9 (6.0)	0.963
ICS, n (% of group)	0	0		2 (13)	0.034	7 (78)	<0.001
FEV₁%^†	93.9 (9.3)	99.7 (8.9)	0.014	97.8 (9.5)	0.145	95.8 (9.5)	0.555
FEF_25–75%^†	89.9 (23.9)	88.6 (19.1)	0.819	86.0 (22.9)	0.568	84.4 (20.2)	0.514
FEV₁ /FVC ratio^†	82.8 (7.5)	80.6 (4.9)	0.221	79.7 (7.7)	0.159	78.8 (7.3)	0.135
DRS to methacholine^*	6.0 (1.7, 25.5)	4.9 (1.1, 13.4)	0.378	4.1 (1.5, 18.1)	0.910	4.4 (2.2, 13.8)	0.923

^*Median (inter quartile range), ^†mean (standard deviation). ICS, inhalation corticosteroid last 12 months before follow up; FEV₁%, forced expiratory volume in first second as percentage of predicted; FEF_25–75%, forced expiratory flow between 25-75% of the forced vital capacity (FVC); DRS, dose response slope. For missing data, see text. P-values assess comparisons with the healthy group.
Bold values indicate significance at the 0.05 level.

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