Skip to main content

Table 2 Experiment 1: Cytokine and chemokine analysis in lung perfusate at the end of MV

From: The effects of exogenous surfactant administration on ventilation-induced inflammation in mouse models of lung injury

 

Mechanical ventilation

Mediator (pg/ml)

No treatment

bLES

Eotaxin

42.8 ± 3.6

42.7 ± 6.5

G-CSF

9.5 ± 2.0

11.7 ± 2.8

GM-CSF

1.6 ± 1.6

5.1 ± 2.4

IL-6

520.6 ± 117.2

463.0 ± 75.2

IL-1 β

0.8 ± 0.4

0.6 ± 0.3

KC

868.6 ± 254.3

853.8 ± 222.6

LIX

71.3 ± 14.8

66.1 ± 11.4

MCP-1

12.2 ± 2.7

7.5 ± 1.8

MIP-2

753.9 ± 193.8

658.5 ± 167.8

TNF-α

23.4 ± 7.8

17.4 ± 7.0

IP-10

39.9 ± 5.4

37.8 ± 6.2

  1. G-CSF = granulocyte colony-stimulating factor, GM-CSF = granulocyte-macrophage CSF, IL-6 = interleukin-6, IP-10 = interferon-γ-induced protein 10, KC = keratinocyte chemoattractant, LIX = lipopolysaccharide-induced CXC chemokine, MCP-1 = monocyte chemotactic protein-1, MIP-2 = macrophage inflammatory protein 2 and TNF-α = tumor necrosis factor-alpha.
  2. Data are expressed as mean ± SEM; n = 6 per group.