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Table 2 Experiment 1: Cytokine and chemokine analysis in lung perfusate at the end of MV

From: The effects of exogenous surfactant administration on ventilation-induced inflammation in mouse models of lung injury

  Mechanical ventilation
Mediator (pg/ml) No treatment bLES
Eotaxin 42.8 ± 3.6 42.7 ± 6.5
G-CSF 9.5 ± 2.0 11.7 ± 2.8
GM-CSF 1.6 ± 1.6 5.1 ± 2.4
IL-6 520.6 ± 117.2 463.0 ± 75.2
IL-1 β 0.8 ± 0.4 0.6 ± 0.3
KC 868.6 ± 254.3 853.8 ± 222.6
LIX 71.3 ± 14.8 66.1 ± 11.4
MCP-1 12.2 ± 2.7 7.5 ± 1.8
MIP-2 753.9 ± 193.8 658.5 ± 167.8
TNF-α 23.4 ± 7.8 17.4 ± 7.0
IP-10 39.9 ± 5.4 37.8 ± 6.2
  1. G-CSF = granulocyte colony-stimulating factor, GM-CSF = granulocyte-macrophage CSF, IL-6 = interleukin-6, IP-10 = interferon-γ-induced protein 10, KC = keratinocyte chemoattractant, LIX = lipopolysaccharide-induced CXC chemokine, MCP-1 = monocyte chemotactic protein-1, MIP-2 = macrophage inflammatory protein 2 and TNF-α = tumor necrosis factor-alpha.
  2. Data are expressed as mean ± SEM; n = 6 per group.