From: Clinical, economic, and humanistic burden of asthma in Canada: a systematic review
Study | Number of patients | Patient descriptor | Year | Hospitalizations for asthma | |
---|---|---|---|---|---|
Per patient per year | Per 1000 patients per year | ||||
Children | |||||
Blais et al. 2011 [43] | 7,494 | ≥1 exacerbations in the year prior to treatment initiation, ICS | 1998-2005 | 0.03 | |
≥1 exacerbations in the year prior to treatment initiation, LTRA | 0.06 | ||||
19,861 | No exacerbation in the year prior to treatment initiation: ICS | 0.005 | |||
No exacerbation in the year prior to treatment initiation: LTRA | 0.003 | ||||
Ungar et al. 2011 [21] | 490 | Asthmatic children | 2000-2003 | 0.25§ | |
To et al. 2008 [24] | 56,737 | 0-2 years | 1998/1999 | 86.7 | |
99,163 | 3-5 years | 27.3 | |||
141,305 | 6-9 years | 10.9 | |||
297,205 | Overall | 30.9 | |||
To et al. 2007 [26] | 34,216 | Persistent asthma | 1994-2006 | 63* | |
Remission asthma | 39* | ||||
Overall | 52* | ||||
Ungar et al. 2001 [33] | 339 | Asthma children | 1995 | 1 | |
Adults | |||||
Sadatsafavi et al. 2010 [10] | 158,516 | Narrow asthma definition€ | 1996-2000 | 0.016 | |
Broad asthma definition¥ | 0.03 | ||||
Lemiere et al. 2007 [25] | 351 (WEA: 145, OA: 206) | WRA | 2001-2003 | 0.04(0.2) | |
NWRA | 0.008(0.7) | ||||
Anis et al. 2001 [38] | 4,671 | Appropriate use† | 1995 | 0.07(0.34) | |
763 | Inappropriate use‡ | 0.11(0.42) | |||
All ages | |||||
Disano et al. 2010 [22] | NR | High SES | 2003-2006 | 1.61** | |
Average SES | 1.95** | ||||
Low SES | 2.7** | ||||
Klomp et al. 2008 [36] | 24,616 (24,180 of whom were still alive and living in the region the following year) | Asthma patients | 2002/2003 and 2003/2004 | 10.9 | |
Lougheed et al. 2006 [28] | 574,304 children and 1,194,095 adults in Ontario | Patients with an ED disposition diagnosis of asthma in a stratified sample of 16 hospitals | 2001-2002 | 108 (10.8%) children; 69 (6.9%) adults | |
Suissa et al. 2002 [41] | 30,569 | Source cohort†† | 1975-1997 | 48 | |
4,673 | Full cohort‡‡ | 42.4 | |||
Seung et al. 2005 [42] | NR | Asthma patients | 2004 | 1.43** |