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Table 1 Demographics, signs and symptoms, risk factors and prior medical history by year for 850 patients undergoing CT angiography

From: Finding an alternative diagnosis does not justify increased use of CT-pulmonary angiography

Characteristics

2000

2005

2008

Total

p

n

74

383

393

850

 

Demographics

     

 Age (years) (mean ± SD)

66.8 ± 16.8

62.9 ± 17

60 ± 19.3

61.9 ± 18.2

0.004

 Female (%)

59.5

65

67.9

65.9

0.33

 Females < 40 years (%)

6.8

7.8

16.5

11.8

0.004

 Body mass index (kg/m2) (mean ± SD)

27.3 ± 5.5

27.4 ± 7.2

27.8 ± 6.2

27.6 ± 6.7

0.760

Signs and symptoms

     

 Shortness of breath (%)

79.7

63.7

62.3

64.5

0.015

 Chest pain (%)

27

38.9

50.1

43.1

<0.001

 Palpitations (%)

5.5

1.3

3.3

2.6

0.06

 Syncope (%)

2.7

1

3.8

2.5

0.04

 Hypoxia (%)

13.7

6.5

10.2

8.8

0.06

 Cough (%)

9.5

9.9

12

10.8

0.60

 Hemoptysis (%)

1.4

0.3

3.6

1.9

0.003

 Lower extremity pain (%)

4.1

0

5.9

3.1

<0.001

 Leg edema/tenderness (%)

1.4

0

8.9

4.2

<0.001

 Other (%)

14.9

10.2

27.2

18.5

<0.001

 Systolic blood pressure (mmHg)

128 ± 27

131 ± 23

129 ± 22

130 ± 23

0.389

 Diastolic blood pressure (mmHg)

73 ± 13

75 ± 15

73 ± 14

74 ± 14

0.19

 Respiratory rate (/min)

23.8 ± 7.5

20.7 ± 6

20 ± 5.7

20.6 ± 6

<0.001

 Oxygen saturation (%)

92.7 ± 6.8

94.1 ± 6

95.3 ± 9.6

94.5 ± 8

0.01

 Requiring supplemental O2 (%)

40.5

22.1

19

22.3

<0.001

Risk factors for thrombosis (%)

     

 Immobility

31.1

24.8

15.8

21.2

0.001

 Active malignancy

31.1

29.8

22.1

26.4

0.03

 Hospitalized in the prior 4 weeks

38.4

34.7

28.3

32.1

0.08

 Surgery in the prior 4 weeks

25.7

17

16.3

17.4

0.14

 Prior PE or DVT

17.6

9.4

12.5

11.5

0.01

 Pregnant

1.4

1.6

5.1

3.2

0.01

 Known hypercoagulable disorder

0

1.6

1

1.2

0.48

 On estrogen therapy

6.8

1.8

3.6

3.1

0.06

Prior medical history (%)

     

 Any lung disease

29.7

26.4

24.4

25.8

0.58

 Hypertension

48.7

16.5

51.2

35.3

<0.001

 Coronary artery disease

27

18.5

23.2

21.4

0.14

 Congestive heart failure

18.9

6

6.6

7.4

<0.001

 Other cardiac disease

25.8

6.8

13.5

11.5

0.26

 Dialysis

0

1.3

2.3

1.7

0.28

 Transferred from another institution

8.2

11.5

8.4

9.8

0.31