| Quartile 1 (4.1 – 8.04 m/s) n = 38 | Quartile 2 (8.05 – 9.69 m/s) n = 36 | Quartile 3 (9.7 – 11.74 m/s) n = 41 | Quartile 4 (>11.75 m/s) n = 38 |
---|---|---|---|---|
Age (years) ¥ | 59.4 (7.2) | 61.7 (6.9) | 63.6 (7.7)* | 68.1 (8.4)** |
Male, n (%) | 20 (53) | 17 (47) | 22 (54) | 24 (63) |
Race, Caucasian, n (%) | 34 (89) | 33 (92) | 39 (95) | 36 (95) |
BMI (kg/m2) | 26.4 (4.8) | 27.2 (4.9) | 26.1 (4.6) | 28.0 (4.7) |
Current smoker, n (%) | 13 (34) | 18 (50) | 20 (49) | 26 (68)* |
Total pack-years | 55.32 (29.81) | 48.75 (23.67) | 55.56 (20.59) | 66.92 (38.69) |
FEV1 (%predicted) | 52.99 (15.17) | 59.56 (13.43) | 55.18 (15.36) | 54.26 (15.97) |
FEV1 (L) | 1.61 (0.62) | 1.76 (0.62) | 1.60 (0.58) | 1.54 (0.57) |
Cardiovascular disease, n (%) | 10 (26) | 8 (22) | 14 (34) | 21 (55)* |
Diabetes mellitus, n (%) | 8 (21) | 11 (31) | 10 (24) | 17 (45) |
Heart Rate (per minute) | 69.6 (10.3) | 69.1 (11.1) | 68.5 (13.4) | 71.2 (8.8) |
Systolic blood pressure (mmHg) ¥ | 120.5 (17.3) | 125.9 (14.1) | 128.8 (17.2)* | 134.7 (16.8)** |
Diastolic blood pressure (mmHg) | 75.9 (10.1) | 78.1 (11.1) | 75.7 (8.3) | 78.6 (9.3) |
Log TAC | 6.28 (2.16) | 6.17 (2.17) | 7.20 (1.97)* | 7.64 (1.31)** |
Log CAC | 5.43 (1.80) | 5.10 (2.44) | 5.71 (1.97) | 5.66 (2.05) |
aPWV (m/s) | 6.7 (1.1) | 8.8 (0.4) | 10.6 (0.5) | 13.7 (2.1) |
%emphysema on CT | 7.2 (9.1) | 6.6 (9.3) | 11.1 (14.1) | 10.3 (11.7) |
LDL cholesterol (mmol/L) | 2.56 (1.04) | 2.66 (0.98) | 2.61 (0.93) | 2.60 (1.03) |
HDL cholesterol (mmol/L) | 1.42 (0.53) | 1.51 (0.68) | 1.52 (0.47) | 1.35 (0.41) |
Total cholesterol (mmol/L) | 4.75 (0.97) | 4.86 (1.10) | 4.93 (1.18) | 4.70 (1.16) |
Log hsCRP (mg/L) | 0.95 (0.88) | 0.76 (0.95) | 1.08 (1.02) | 1.28 (1.12) |
Log fibrinogen (mg/dl) | 1.10 (0.21) | 0.98 (0.28)* | 1.07 (0.29) | 1.08 (0.20) |