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Table 3 Comparison of variables across aPWV quartiles

From: Determinants of arterial stiffness in COPD

 

Quartile 1 (4.1 – 8.04 m/s) n = 38

Quartile 2 (8.05 – 9.69 m/s) n = 36

Quartile 3 (9.7 – 11.74 m/s) n = 41

Quartile 4 (>11.75 m/s) n = 38

Age (years) ¥

59.4 (7.2)

61.7 (6.9)

63.6 (7.7)*

68.1 (8.4)**

Male, n (%)

20 (53)

17 (47)

22 (54)

24 (63)

Race, Caucasian, n (%)

34 (89)

33 (92)

39 (95)

36 (95)

BMI (kg/m2)

26.4 (4.8)

27.2 (4.9)

26.1 (4.6)

28.0 (4.7)

Current smoker, n (%)

13 (34)

18 (50)

20 (49)

26 (68)*

Total pack-years

55.32 (29.81)

48.75 (23.67)

55.56 (20.59)

66.92 (38.69)

FEV1 (%predicted)

52.99 (15.17)

59.56 (13.43)

55.18 (15.36)

54.26 (15.97)

FEV1 (L)

1.61 (0.62)

1.76 (0.62)

1.60 (0.58)

1.54 (0.57)

Cardiovascular disease, n (%)

10 (26)

8 (22)

14 (34)

21 (55)*

Diabetes mellitus, n (%)

8 (21)

11 (31)

10 (24)

17 (45)

Heart Rate (per minute)

69.6 (10.3)

69.1 (11.1)

68.5 (13.4)

71.2 (8.8)

Systolic blood pressure (mmHg) ¥

120.5 (17.3)

125.9 (14.1)

128.8 (17.2)*

134.7 (16.8)**

Diastolic blood pressure (mmHg)

75.9 (10.1)

78.1 (11.1)

75.7 (8.3)

78.6 (9.3)

Log TAC

6.28 (2.16)

6.17 (2.17)

7.20 (1.97)*

7.64 (1.31)**

Log CAC

5.43 (1.80)

5.10 (2.44)

5.71 (1.97)

5.66 (2.05)

aPWV (m/s)

6.7 (1.1)

8.8 (0.4)

10.6 (0.5)

13.7 (2.1)

%emphysema on CT

7.2 (9.1)

6.6 (9.3)

11.1 (14.1)

10.3 (11.7)

LDL cholesterol (mmol/L)

2.56 (1.04)

2.66 (0.98)

2.61 (0.93)

2.60 (1.03)

HDL cholesterol (mmol/L)

1.42 (0.53)

1.51 (0.68)

1.52 (0.47)

1.35 (0.41)

Total cholesterol (mmol/L)

4.75 (0.97)

4.86 (1.10)

4.93 (1.18)

4.70 (1.16)

Log hsCRP (mg/L)

0.95 (0.88)

0.76 (0.95)

1.08 (1.02)

1.28 (1.12)

Log fibrinogen (mg/dl)

1.10 (0.21)

0.98 (0.28)*

1.07 (0.29)

1.08 (0.20)

  1. *p<0.05. ** p<0.01 for quartiles compared with quartile 1.
  2. ¥ p<0.01 on multivariate analyses for quartile 4 compared with quartile 1.
  3. All values expressed as mean (standard deviation) unless otherwise specified.
  4. Definition of abbreviations: BMI body mass index, FEV 1 forced expiratory volume in the first 1 second, TAC thoracic aortic calcification, CAC coronary arterial calcification, aPWV aortic pulse wave velocity, CT computed tomography, LDL low density lipoprotein, HDL high density lipoprotein, hsCRP high sensitivity C-reactive protein.