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Table 4 Fractional composition of methyl-D 9 -choline incorporation into newly synthesized PC at 24 and 48 hours

From: Phospholipid composition and kinetics in different endobronchial fractions from healthy volunteers

Newly synthesized D9-choline labelled molecular PC composition at 24 and 48 hours

 

24 hours

48 hours

PC species (%)

BALF

TW

IS

BALF

TW

IS

PC16:0/14:0

10.0 ±2.5

7.8 ±2.8

7.9 ±3.2

8.8 ±1.0

7.5 ±1.0

7.3 ±1.9

PC16:0a/16:0

2.6 ±0.6

2.4 ±0.6

4.0 ±2.9

2.3 ±0.5

2.3 ±0.5

3.5 ±0.9

PC16:0/16:1

10.0 ± 2.5

8.9 ±2.4

7.03 ±2.0

9.3 ±1.7

8.1 ±2.1

7.6 ±2.0

PC16:0/16:0

46.9 ±3.0

39.4 ±8.5

22.5 ±7.9

50.6 ±3.8

45.4 ±7.3

40.4 ±5.8

PC16:0/18:2

6.9 ±1.8

8.32 ±2.7

12.6 ±2.3

6.1 ±1.4

8.0 ±2.4

8.3 ±0.9

PC16:0/18:1

14.5 ±1.7

17.5 ±2.8

*18.2 ±4.5

13.9 ±1.9

14.9 ±1.8

15.9 ±2.2

PC16:0/20:4

1.5 ±0.6

2.2 ±0.9

4.5 ±1.7

1.5 ±0.5

2.0 ±0.7

2.1 ±1.0

PC18:1/18:2

1.9 ±0.7

3.1 ±1.5

*5.8 ±1.9

2.0 ±0.6

2.7 ±0.9

3.5 ±1.4

PC18:0/18:2

3.2 ±0.9

5.4 ±2.8

9.1 ±3.0

2.8 ±1.1

4.6 ±2.3

*6.0 ±1.9

PC18:0/18:1

1.3 ±0.6

2.5 ±1.2

*4.7 ±2.3

1.5 ±0.8

2.3 ±1.8

3.3 ±1.1

PC18:1/20:4

0.5 ±0.2

0.9 ±0.5

1.5 ±1.1

0.4 ±0.2

0.7 ±0.4

0.9 ±0.4

PC18:0/20:4

0.7 ±0.4

1.7 ±0.9

2.1 ±0.9

0.7 ±0.5

1.3 ±1.1

1.1 ±0.4

  1. BALF, Bronchoalveolar lavage fluid; TW, Tracheal wash; IS, Induced sputum; PC, Phosphatidylcholine. *P < 0.05, P < 0.01, P < 0.001 for TW and IS compared with BALF calculated by two way analysis of variance, data presented as mean ± SD.