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Table 1 Patients with severe vs moderate clinical severity

From: Flagellin concentrations in expectorations from cystic fibrosis patients

Sex FEV1 FVC PI/PS CFRD BMI IL-8 Flagellin
(% pred.) (% pred.) kg/m2 (ng/100 μg prot) (ng /100 μg protein)
Patients with severe respiratory insufficiency
2 F 30 38 PI N 15.04 2189.72 11.23
3 M 24 55 PI Y 24.77 3163.50 5.76
8 M 44 43 PI N 20.01 3064.52 2.92
9 M 20 39 PI Y 20.68 1866.86 23.29
10 M 40 62 PI Y 16.61 4009.74 33.78
13 M 44 60 PI N 19.35 5851.31 8.58
14 M 37 69 PS N 20.43 966.36 31.53
15 M 30 46 PI N 18.94 7007.48 13.40
16 F 27 37 PI N 21.22 10848.53 60.65
17 M 29 57 PI N 22.40 2754.30 16.75
20 M 43 58 PI N 21.26 2203.66 4.24
21 F 43 58 PI N 20.50 3596.65 6.50
25 F 42 60 PI Y 33.20 4089.03 3.68
31 M 38 58 PI N 21.41 2681.30 7.17
34 F 18 22 PI Y 21.68 3050.02 1.74
35 F 41 54 PS N 19.20 1735.26 6.12
36 F 41 61 PI N 18.26 3764.78 0.64
Mean M: 58.8% 34.76 51.59 PI: 88.2% CFRD: 29.4% 20.88 3696.65 14.00
±SD   8.78 12.11    3.87 2361.02 15.60
Patients with moderate respiratory insufficiency
4 F 66 81 PI N 19.89 1114.53 12.66
5 F 66 79 PI Y 25.33 1680.15 4.80
6 F 64 73 PS N 26.67 2748.14 5.10
7 M 60 68 PI N 22.59 2548.47 5.62
11 F 91 106 PI N 21.64 1832.33 3.41
12 M 59 79 PI Y 25.69 7971.28 2.68
18 F 70 84 PI N 25.81 2289.97 3.62
19 F 73 82 PI Y 17.75 2142.72 30.01
22 M 75 108 PI N 19.59 4286.10 3.82
23 F 55 89 PI Y 20.26 1648.29 13.88
24 M 46 74 PI Y 20.86 3194.50 4.50
26 M 55 55 PI Y 23.66 3217.85 32.80
37 F 57 82 PI Y 23.31 4453.10 1.07
38 M 76 91 PI N 22.99 3437.08 2.73
Mean M: 42.8% 65.21 82.21 PI: 92.9% CFRD: 50% 22.57 3040.32 9.05
±SD   11.35 13.80    2.70 1725.97 10.15
  1. Comparison of two groups of patients, a group with clinical severity defined as severe (18 patients), and a group with clinical severity defined as moderate (13 patients).
  2. FEV1 (% pred.) and FCV (% pred.) are forced expiratory volume in one second and forced vital capacity (expressed as percentage of the predicted value), respectively. Pancreatic insufficiency (PI) vs pancreatic sufficiency (PS); cystic fibrosis-related diabetes (CFRD); Body mass index (BMI).