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Table 1 Patients with severe vs moderate clinical severity

From: Flagellin concentrations in expectorations from cystic fibrosis patients

Sex

FEV1

FVC

PI/PS

CFRD

BMI

IL-8

Flagellin

(% pred.)

(% pred.)

kg/m2

(ng/100 μg prot)

(ng /100 μg protein)

Patients with severe respiratory insufficiency

2

F

30

38

PI

N

15.04

2189.72

11.23

3

M

24

55

PI

Y

24.77

3163.50

5.76

8

M

44

43

PI

N

20.01

3064.52

2.92

9

M

20

39

PI

Y

20.68

1866.86

23.29

10

M

40

62

PI

Y

16.61

4009.74

33.78

13

M

44

60

PI

N

19.35

5851.31

8.58

14

M

37

69

PS

N

20.43

966.36

31.53

15

M

30

46

PI

N

18.94

7007.48

13.40

16

F

27

37

PI

N

21.22

10848.53

60.65

17

M

29

57

PI

N

22.40

2754.30

16.75

20

M

43

58

PI

N

21.26

2203.66

4.24

21

F

43

58

PI

N

20.50

3596.65

6.50

25

F

42

60

PI

Y

33.20

4089.03

3.68

31

M

38

58

PI

N

21.41

2681.30

7.17

34

F

18

22

PI

Y

21.68

3050.02

1.74

35

F

41

54

PS

N

19.20

1735.26

6.12

36

F

41

61

PI

N

18.26

3764.78

0.64

Mean

M: 58.8%

34.76

51.59

PI: 88.2%

CFRD: 29.4%

20.88

3696.65

14.00

±SD

 

8.78

12.11

  

3.87

2361.02

15.60

Patients with moderate respiratory insufficiency

4

F

66

81

PI

N

19.89

1114.53

12.66

5

F

66

79

PI

Y

25.33

1680.15

4.80

6

F

64

73

PS

N

26.67

2748.14

5.10

7

M

60

68

PI

N

22.59

2548.47

5.62

11

F

91

106

PI

N

21.64

1832.33

3.41

12

M

59

79

PI

Y

25.69

7971.28

2.68

18

F

70

84

PI

N

25.81

2289.97

3.62

19

F

73

82

PI

Y

17.75

2142.72

30.01

22

M

75

108

PI

N

19.59

4286.10

3.82

23

F

55

89

PI

Y

20.26

1648.29

13.88

24

M

46

74

PI

Y

20.86

3194.50

4.50

26

M

55

55

PI

Y

23.66

3217.85

32.80

37

F

57

82

PI

Y

23.31

4453.10

1.07

38

M

76

91

PI

N

22.99

3437.08

2.73

Mean

M: 42.8%

65.21

82.21

PI: 92.9%

CFRD: 50%

22.57

3040.32

9.05

±SD

 

11.35

13.80

  

2.70

1725.97

10.15

  1. Comparison of two groups of patients, a group with clinical severity defined as severe (18 patients), and a group with clinical severity defined as moderate (13 patients).
  2. FEV1 (% pred.) and FCV (% pred.) are forced expiratory volume in one second and forced vital capacity (expressed as percentage of the predicted value), respectively. Pancreatic insufficiency (PI) vs pancreatic sufficiency (PS); cystic fibrosis-related diabetes (CFRD); Body mass index (BMI).