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Table 2 Patients with high vs low flagellin concentrations

From: Flagellin concentrations in expectorations from cystic fibrosis patients

Sex

Status

Mucoid/non mucoid

FEV1

FVC

Total proteins

IL-8

Flagellin

Stable/Exacerbation

(% pred.)

(% pred.)

(mg/ml)

(ng/100 μg prot)

(ng/100 μg protein)

Patients with flagellin sputum < 10 ng/100 μg protein

3

M

Stable

Non mucoid

24

55

6.58

3163.50

5.76

5

F

Stable

Non mucoid

66

79

3.21

1680.15

4.80

6

F

Exacerbation

Mucoid

64

73

4.57

2748.14

5.10

7

M

Stable

Non mucoid

60

68

9.34

2548.47

5.62

8

M

Exacerbation

Non mucoid

44

43

3.84

3064.52

2.92

11

F

Stable

Non mucoid

91

106

3.15

1832.33

3.41

12

M

Stable

Non mucoid

59

79

4.39

7971.28

2.68

13

M

Stable

Non mucoid

44

60

11.8

5851.31

8.58

18

F

Stable

Non mucoid

70

84

4.17

2289.97

3.62

20

M

Stable

Non mucoid

43

58

8.68

2203.66

4.24

21

F

Stable

Mucoid

43

58

5.91

3596.65

6.50

22

M

Stable

Non mucoid

75

108

5.87

4286.10

3.82

24

M

Stable

Non mucoid

46

74

7.25

3194.50

4.50

25

F

Stable

Non mucoid

42

60

4.91

4089.03

3.68

31

M

Stable

Mucoid

38

58

4.70

2681.30

7.17

34

F

Exacerbation

Non mucoid

18

22

4.22

3050.02

1.74

35

F

Stable

Non mucoid

41

54

7.83

1735.26

6.12

36

F

Exacerbation

Non mucoid

41

61

6.71

3764.78

0.64

37

F

Stable

Mucoid

57

82

8.93

4453.10

1.07

38

M

Stable

Non mucoid

76

91

6.59

3437.08

2.73

Mean

M: 50%

 

non.mucoid:.80%

52.10

68.65

6.13

3382.06

4.24

±SD

  

18.11

20.39

2.30

1491.93

2.03

Patients with flagellin sputum > 10 ng/100 μg protein

2

F

Stable

Mucoid

30

38

7.90

2189.72

11.23

4

F

Stable

Non mucoid

66

81

3.25

1114.53

12.66

9

M

Stable

Mucoid

20

39

8.22

1866.86

23.29

10

M

Stable

Mucoid

40

62

4.11

4009.74

33.78

14

M

Stable

Non mucoid

37

69

5.38

966.36

31.53

15

M

Stable

Non mucoid

30

46

6.42

7007.48

13.40

16

F

Exacerbation

Non mucoid

27

37

5.87

10848.53

60.65

17

M

Stable

Non mucoid

29

57

2.79

2754.30

16.75

19

F

Stable

Non mucoid

73

82

5.14

2142.72

30.01

23

F

Stable

Mucoid

55

89

6.81

1648.29

13.88

26

M

Stable

Non mucoid

55

55

8.44

3217.85

32.80

Mean

M: 54.5%

 

Non mucoid:.63.6%

42.00

59.55

5.85

3433.31

25.45

±SD

  

17.52

18.80

1.94

2981.86

14.65

  1. Comparison of two groups of patients, a group with flagellin concentrations lower than 10 ng/100 μg proteins (20 patients), and a group with flagellin concentrations higher than 10 ng/100 μg proteins (11 patients).
  2. FEV1 (% pred.) and FCV (% pred.) are forced expiratory volume in one second and forced vital capacity (expressed as percentage of the predicted value), respectively.