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Table 2 Patients with high vs low flagellin concentrations

From: Flagellin concentrations in expectorations from cystic fibrosis patients

Sex Status Mucoid/non mucoid FEV1 FVC Total proteins IL-8 Flagellin
Stable/Exacerbation (% pred.) (% pred.) (mg/ml) (ng/100 μg prot) (ng/100 μg protein)
Patients with flagellin sputum < 10 ng/100 μg protein
3 M Stable Non mucoid 24 55 6.58 3163.50 5.76
5 F Stable Non mucoid 66 79 3.21 1680.15 4.80
6 F Exacerbation Mucoid 64 73 4.57 2748.14 5.10
7 M Stable Non mucoid 60 68 9.34 2548.47 5.62
8 M Exacerbation Non mucoid 44 43 3.84 3064.52 2.92
11 F Stable Non mucoid 91 106 3.15 1832.33 3.41
12 M Stable Non mucoid 59 79 4.39 7971.28 2.68
13 M Stable Non mucoid 44 60 11.8 5851.31 8.58
18 F Stable Non mucoid 70 84 4.17 2289.97 3.62
20 M Stable Non mucoid 43 58 8.68 2203.66 4.24
21 F Stable Mucoid 43 58 5.91 3596.65 6.50
22 M Stable Non mucoid 75 108 5.87 4286.10 3.82
24 M Stable Non mucoid 46 74 7.25 3194.50 4.50
25 F Stable Non mucoid 42 60 4.91 4089.03 3.68
31 M Stable Mucoid 38 58 4.70 2681.30 7.17
34 F Exacerbation Non mucoid 18 22 4.22 3050.02 1.74
35 F Stable Non mucoid 41 54 7.83 1735.26 6.12
36 F Exacerbation Non mucoid 41 61 6.71 3764.78 0.64
37 F Stable Mucoid 57 82 8.93 4453.10 1.07
38 M Stable Non mucoid 76 91 6.59 3437.08 2.73
Mean M: 50%   non.mucoid:.80% 52.10 68.65 6.13 3382.06 4.24
±SD    18.11 20.39 2.30 1491.93 2.03
Patients with flagellin sputum > 10 ng/100 μg protein
2 F Stable Mucoid 30 38 7.90 2189.72 11.23
4 F Stable Non mucoid 66 81 3.25 1114.53 12.66
9 M Stable Mucoid 20 39 8.22 1866.86 23.29
10 M Stable Mucoid 40 62 4.11 4009.74 33.78
14 M Stable Non mucoid 37 69 5.38 966.36 31.53
15 M Stable Non mucoid 30 46 6.42 7007.48 13.40
16 F Exacerbation Non mucoid 27 37 5.87 10848.53 60.65
17 M Stable Non mucoid 29 57 2.79 2754.30 16.75
19 F Stable Non mucoid 73 82 5.14 2142.72 30.01
23 F Stable Mucoid 55 89 6.81 1648.29 13.88
26 M Stable Non mucoid 55 55 8.44 3217.85 32.80
Mean M: 54.5%   Non mucoid:.63.6% 42.00 59.55 5.85 3433.31 25.45
±SD    17.52 18.80 1.94 2981.86 14.65
  1. Comparison of two groups of patients, a group with flagellin concentrations lower than 10 ng/100 μg proteins (20 patients), and a group with flagellin concentrations higher than 10 ng/100 μg proteins (11 patients).
  2. FEV1 (% pred.) and FCV (% pred.) are forced expiratory volume in one second and forced vital capacity (expressed as percentage of the predicted value), respectively.