Patient characteristics | N of patients analyzed | % patients with poor HRQoL | Crude OR | 95%CI | P-value | Adjusted OR | 95%CI | P-value |
---|---|---|---|---|---|---|---|---|
Gender | ||||||||
Male | 422 | 10.8 | 1.00 | |||||
Female | 225 | 15.4 | 1.51 | 0.97-2.35 | NS | 2.11 | 1.27-3.51 | 0.004 |
Age at recruitment | ||||||||
<60 years | 215 | 13.5 | 1.00 | |||||
61–68 years | 274 | 14.2 | 1.06 | 0.64-1.79 | NS | |||
>69 years | 250 | 9.6 | 0.68 | 0.38-1.21 | NS | |||
FEV1 baseline % of predicted | ||||||||
>80 | 95 | 9.5 | 1.00 | |||||
65–80 | 185 | 4.9 | 0.50 | 0.17-1.43 | NS | 0.54 | 0.18-1.63 | 0.27 |
40–64 | 323 | 13.3 | 1.47 | 0.63-3.43 | NS | 2.48 | 0.99-5.95 | 0.05 |
<40 | 136 | 22.9 | 2.84 | 1.19-6.79 | 0.02 | 5.17 | 2.03-13.17 | 0.001 |
Smoking cessation succeed | ||||||||
Yes | 358 | 11.2 | 1.00 | |||||
No | 281 | 14.2 | 1.32 | 0.83-2.11 | NS | |||
BMI units | ||||||||
<19 | 33 | 34.3 | - | - | - | |||
19–25 | 251 | 4.5 | 1.00 | |||||
>25-30 | 275 | 37.6 | 0.64 | 0.37-1.07 | NS | |||
>30 | 173 | 23.6 | 0.95 | 0.54-1.64 | NS | |||
Diabetes | ||||||||
No | 628 | 11.9 | 1.00 | |||||
Yes | 111 | 15.3 | 1.33 | 0.75-2.36 | NS | |||
Cardiovascular Disease1 | ||||||||
No | 532 | 13.3 | 1.00 | |||||
Yes | 207 | 10.1 | 0.73 | 0.44-1.23 | NS | |||
Hypertension | ||||||||
No | 439 | 12.3 | 1.00 | |||||
Yes | 300 | 12.7 | 1.03 | 0.66-1.61 | NS | |||
Atrial Fibrillation | -2 | |||||||
No | 474 | 14.1 | 1.00 | |||||
Yes | 31 | 29.0 | 2.49 | 1.10-5.63 | 0.03 | |||
Diffusing capacity | ||||||||
Normal | 221 | 11.8 | 1.00 | |||||
Mild/moderately decrease | 89 | 11.2 | 0.95 | 0.44-2.06 | NS | |||
Severe decrease | 103 | 16.5 | 1.48 | 0.77-2.87 | NS | |||
Cancer | ||||||||
No | 695 | 12.4 | 1.00 | |||||
Yes | 44 | 13.6 | 1.12 | 0.46-2.72 | NS | |||
Psychiatric conditions | ||||||||
No | 493 | 9.9 | 1.00 | |||||
Yes | 240 | 17.1 | 1.87 | 1.19-2.92 | 0.006 | 1.99 | 1.21-3.29 | 0.007 |
Alcohol abuse | ||||||||
No | 629 | 10.5 | 1.00 | |||||
Yes | 110 | 23.6 | 2.64 | 1.59-4.39 | <0.001 | 3.02 | 1.65-5.51 | 0.001 |