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Table 1 Comparison of clinical characteristics among the CPFE, IPF-alone, and emphysema-alone groups

From: An autopsy study of combined pulmonary fibrosis and emphysema: correlations among clinical, radiological, and pathological features

 

CPFE

IPF

Emphysema

 
 

(n = 22)

(n = 8)

(n = 17)

p-value

Age, years

    

Median

73.5

74

78

0.6949

Range

60–95

55–88

50–84

 

Gender, F/M

0/22

1/7

2/15

0.244

Smoking history, pack years

    

Median

64

43

75

0.6405

Range

20–200

30–120

15–150

 

Pulmonary function test

    

VC

2.52 ± 0.72

2.34 ± 0.86

2.85 ± 0.61

0.5175

%VC

83.1 ± 22.1

68.0 ± 27.7

87.0 ± 12.4

0.2902

FEV1

2.01 ± 0.19

1.60 ± 0.24

1.57 ± 0.22

0.281

FEV1/FVC,%

76.8 ± 3.31

81.8 ± 4.45

55.6 ± 4.06

0.0007

DLCO

6.30 ± 3.89

9.68 ± 3.65

15.45 ± 6.34

0.0149

%DLCO

36.6 ± 17.5

57.1 ± 27.4

102.5 ± 58.1

0.0153

DLCO/VA

1.96 ± 0.77

2.97 ± 0.26

3.06 ± 1.48

0.1428

%DLCO/VA

44.0 ± 16.8

69.1 ± 10.1

69.3 ± 30.6

0.0988

Treatment for IP

    

Corticosteroids

14 (63.6%)

6 (75%)

-

0.452

Immunosuppressive agent

1 (4.5%)

0

-

0.733

Long-term oxygen

5 (22.7%)

1 (12.5%)

-

0.48

Cause of death

    

Lung cancer

9 (40.9%)

1 (12.5%)

13 (81.3%)

0.007

Acute exacerbation of IP

6 (27.2%)

5 (62.5%)

-

0.091

Infection

4 (18.1%)

1 (12.5%)

1 (6.3%)

0.521

Heart failure

2 (9.1%)

0

2 (12.5%)

0.611

Other causes

1 (4.5%)

1 (12.5%)

1 (6.3%)

0.729

  1. CPFE, combined pulmonary fibrosis and emphysema.
  2. IPF, idiopathic pulmonary fibrosis; IP, interstitial pneumonia.
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BMC Pulmonary Medicine

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