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Figure 1 | BMC Pulmonary Medicine

Figure 1

From: Inflammatory cytokine response to exercise in alpha-1-antitrypsin deficient COPD patients ‘on’ or ‘off’ augmentation therapy

Figure 1

Arterial serum levels of IL-1β, IL-6, TNFα and CRP obtained under resting conditions (black bar), every 10 minutes during 1-hour single-leg knee extensor exercise at 50% of maximal exercise capacity (gray bars), and every 30 minutes (up to 4 hours) during recovery post exercise (white bars), in COPD individuals with alpha-1 antitrypsin deficiency receiving augmentation therapy (AATD + AUG), AATD individuals not receiving augmentation therapy (AATD-AUG), AATD individuals with normal pulmonary function (AATD PFTnorm), non-AATD COPD patients (COPD), and age-/activity-matched controls with no lung disease (Healthy). Significant ANOVA main effect for group differences are shown above each graph. In all cases, significance is determined as p < 0.05.

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