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Table 2 Comparison between adherence groups for health outcomes measured during the one-year study

From: Treatment adherence and health outcomes in patients with bronchiectasis

  Inhaled antibiotics   Other respiratory medicines   Airway clearance  
(n = 61a)   (n = 68b)   (n = 69c)
  Adherent (n = 32) Non-adherent (n = 29) p Adherent (n = 37) Non-adherent (n = 31) p Adherent (n = 27) Non-adherent (n = 42) p
Pulmonary exacerbationsd 2.6 ± 2 4.0 ± 2 0.00* 3.1 ± 2.2 3.3 ± 2.3 0.75 3.1 ± 2.2 3.2 ± 2.2 0.84
FEV1, L at 12 months 1.36 ± 0.54 1.29 ± 0.51 0.61 1.35 ± 0.59 1.35 ± 0.50 0.97 1.29 ± 0.44 1.41 ± 0.61 0.40
FEV1,% predicted at 12 months 65 ± 28 56 ± 23 0.22 63 ± 30 63 ± 22 0.92 65 ± 23 62 ± 29 0.60
QOL-B at 12 months          
Physical Functioning 33 ± 28 31 ± 24 0.77 29 ± 26 39 ± 28 0.13 42 ± 28 29 ± 26 0.05*
Role Functioning 48 ± 27 45 ± 21 0.63 44 ± 24 55 ± 24 0.06 48 ± 23 50 ± 26 0.79
Vitality 39 ± 22 39 ± 20 0.92 40 ± 20 40 ± 22 0.98 39 ± 23 40 ± 20 0.73
Social Functioning 42 ± 28 41 ± 22 0.89 39 ± 26 43 ± 25 0.46 37 ± 22 44 ± 27 0.25
Emotional Functioning 73 ± 21 76 ± 18 0.60 74 ± 20 76 ± 20 0.69 73 ± 23 76 ± 18 0.49
Treatment Burden 59 ± 22 57 ± 21 0.83 61 ± 25 59 ± 20 0.66 54 ± 22 64 ± 22 0.07
Health Perceptions 40 ± 18 39 ± 13 0.80 40 ± 18 42 ± 16 0.71 40 ± 19 41 ± 16 0.79
Respiratory Symptoms 61 ± 21 51 ± 20 0.06 60 ± 22 53 ± 20 0.15 54 ± 20 58 ± 22 0.42
  1. an = 61: 6 withdrawals, 8 without adequate adherence data.
  2. bn = 68: 6 withdrawals, 1 participant not prescribed treatment.
  3. cn = 69: 6 withdrawals.
  4. dinhaled antibiotics: n = 66: 1 participant withdrawal, 8 participants with insufficient data to calculate adherence; other respiratory medicines n = 73: 1 participant withdrawal, 1 not prescribed; airway clearance n = 74: 1 participant withdrawal.
  5. *p < 0.05.
  6. Results are presented as mean ± SD, median (IQR) or percentage.
  7. FEV1: forced expiratory volume in one second.
  8. QOL-B: Quality of Life Questionnaire-Bronchiectasis; scores range 0–100, higher scores indicate better quality of life.