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Table 2 Comparison between adherence groups for health outcomes measured during the one-year study

From: Treatment adherence and health outcomes in patients with bronchiectasis

 

Inhaled antibiotics

 

Other respiratory medicines

 

Airway clearance

 

(n = 61a)

 

(n = 68b)

 

(n = 69c)

 

Adherent (n = 32)

Non-adherent (n = 29)

p

Adherent (n = 37)

Non-adherent (n = 31)

p

Adherent (n = 27)

Non-adherent (n = 42)

p

Pulmonary exacerbationsd

2.6 ± 2

4.0 ± 2

0.00*

3.1 ± 2.2

3.3 ± 2.3

0.75

3.1 ± 2.2

3.2 ± 2.2

0.84

FEV1, L at 12 months

1.36 ± 0.54

1.29 ± 0.51

0.61

1.35 ± 0.59

1.35 ± 0.50

0.97

1.29 ± 0.44

1.41 ± 0.61

0.40

FEV1,% predicted at 12 months

65 ± 28

56 ± 23

0.22

63 ± 30

63 ± 22

0.92

65 ± 23

62 ± 29

0.60

QOL-B at 12 months

         

Physical Functioning

33 ± 28

31 ± 24

0.77

29 ± 26

39 ± 28

0.13

42 ± 28

29 ± 26

0.05*

Role Functioning

48 ± 27

45 ± 21

0.63

44 ± 24

55 ± 24

0.06

48 ± 23

50 ± 26

0.79

Vitality

39 ± 22

39 ± 20

0.92

40 ± 20

40 ± 22

0.98

39 ± 23

40 ± 20

0.73

Social Functioning

42 ± 28

41 ± 22

0.89

39 ± 26

43 ± 25

0.46

37 ± 22

44 ± 27

0.25

Emotional Functioning

73 ± 21

76 ± 18

0.60

74 ± 20

76 ± 20

0.69

73 ± 23

76 ± 18

0.49

Treatment Burden

59 ± 22

57 ± 21

0.83

61 ± 25

59 ± 20

0.66

54 ± 22

64 ± 22

0.07

Health Perceptions

40 ± 18

39 ± 13

0.80

40 ± 18

42 ± 16

0.71

40 ± 19

41 ± 16

0.79

Respiratory Symptoms

61 ± 21

51 ± 20

0.06

60 ± 22

53 ± 20

0.15

54 ± 20

58 ± 22

0.42

  1. an = 61: 6 withdrawals, 8 without adequate adherence data.
  2. bn = 68: 6 withdrawals, 1 participant not prescribed treatment.
  3. cn = 69: 6 withdrawals.
  4. dinhaled antibiotics: n = 66: 1 participant withdrawal, 8 participants with insufficient data to calculate adherence; other respiratory medicines n = 73: 1 participant withdrawal, 1 not prescribed; airway clearance n = 74: 1 participant withdrawal.
  5. *p < 0.05.
  6. Results are presented as mean ± SD, median (IQR) or percentage.
  7. FEV1: forced expiratory volume in one second.
  8. QOL-B: Quality of Life Questionnaire-Bronchiectasis; scores range 0–100, higher scores indicate better quality of life.