From: Treatment adherence and health outcomes in patients with bronchiectasis
Inhaled antibiotics | Other respiratory medicines | Airway clearance | |||||||
---|---|---|---|---|---|---|---|---|---|
(n = 61a) | (n = 68b) | (n = 69c) | |||||||
Adherent (n = 32) | Non-adherent (n = 29) | p | Adherent (n = 37) | Non-adherent (n = 31) | p | Adherent (n = 27) | Non-adherent (n = 42) | p | |
Pulmonary exacerbationsd | 2.6 ± 2 | 4.0 ± 2 | 0.00* | 3.1 ± 2.2 | 3.3 ± 2.3 | 0.75 | 3.1 ± 2.2 | 3.2 ± 2.2 | 0.84 |
FEV1, L at 12 months | 1.36 ± 0.54 | 1.29 ± 0.51 | 0.61 | 1.35 ± 0.59 | 1.35 ± 0.50 | 0.97 | 1.29 ± 0.44 | 1.41 ± 0.61 | 0.40 |
FEV1,% predicted at 12 months | 65 ± 28 | 56 ± 23 | 0.22 | 63 ± 30 | 63 ± 22 | 0.92 | 65 ± 23 | 62 ± 29 | 0.60 |
QOL-B at 12 months | |||||||||
Physical Functioning | 33 ± 28 | 31 ± 24 | 0.77 | 29 ± 26 | 39 ± 28 | 0.13 | 42 ± 28 | 29 ± 26 | 0.05* |
Role Functioning | 48 ± 27 | 45 ± 21 | 0.63 | 44 ± 24 | 55 ± 24 | 0.06 | 48 ± 23 | 50 ± 26 | 0.79 |
Vitality | 39 ± 22 | 39 ± 20 | 0.92 | 40 ± 20 | 40 ± 22 | 0.98 | 39 ± 23 | 40 ± 20 | 0.73 |
Social Functioning | 42 ± 28 | 41 ± 22 | 0.89 | 39 ± 26 | 43 ± 25 | 0.46 | 37 ± 22 | 44 ± 27 | 0.25 |
Emotional Functioning | 73 ± 21 | 76 ± 18 | 0.60 | 74 ± 20 | 76 ± 20 | 0.69 | 73 ± 23 | 76 ± 18 | 0.49 |
Treatment Burden | 59 ± 22 | 57 ± 21 | 0.83 | 61 ± 25 | 59 ± 20 | 0.66 | 54 ± 22 | 64 ± 22 | 0.07 |
Health Perceptions | 40 ± 18 | 39 ± 13 | 0.80 | 40 ± 18 | 42 ± 16 | 0.71 | 40 ± 19 | 41 ± 16 | 0.79 |
Respiratory Symptoms | 61 ± 21 | 51 ± 20 | 0.06 | 60 ± 22 | 53 ± 20 | 0.15 | 54 ± 20 | 58 ± 22 | 0.42 |