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Table 4 Serum TAS, lung GSH content, and anitixoidative enzyme activity a

From: Short-term glutamine supplementation decreases lung inflammation and the receptor for advanced glycation end-products expression in direct acute lung injury in mice

  Unchallenged ALI pvalues from Two-way ANOVAb
Control GLN Control GLN ALI GLN ALI × GLN
Serum TAS (mM) 1.13 ± 0.11 1.11 ± 0.17 1.04 ± 0.07 1.07 ± 0.11 NS. NS. NS.
GSH (μmol/g Lung) 4.57 ± 2.44 4.62 ± 2.72 3.89 ± 2.99 6.42 ± 2.52 NS. NS. NS.
Catalase (unit/mg protein) 29.1 ± 2.4 29.1 ± 2.5 21.3 ± 2.1 22.3 ± 2.4 < 0.001 NS. NS.
GR (unit/g protein) 30.6 ± 3.6 31.5 ± 2.6 27.3 ± 3.3 28.5 ± 2.6 < 0.05 NS. NS.
GST (unit/mg protein) 0.39 ± 0.08 0.41 ± 0.08 0.28 ± 0.04 0.30 ± 0.04 < 0.001 NS. NS.
SOD (unit/mg protein) 3.07 ± 0.26 3.32 ± 0.24 3.23 ± 0.36 3.28 ± 0.47 NS. NS. NS.
Se-GPx (unit/g protein) 44.8 ± 6.4 45.4 ± 9.1 37.4 ± 5.3 43.6 ± 5.4 0.05 NS. NS.
  1. aEach value represents Mean ± S.D., n = 10-12. NS., no significant difference; GSH, glutathione; GR, glutathione reductase; GST, glutathione S-transferase; Se-GPx, se-dependent glutathione peroxidase; SOD, superoxide dismutase; TAS, total antioxidant system.
  2. bThe significance of differences among four groups were analyzed by two-way ANOVA . Values not sharing a same superscript letters in the horizontal row are significantly different from one another by Duncan’s Multiple Range Test (P < 0.05).