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Table 2 Sizes of vesicles and internalized particles

From: Nanoparticle uptake by airway phagocytes after fungal spore challenge in murine allergic asthma and chronic bronchitis

Animals Single NP Vesicle RV/P Cluster Vesicle RV/P Cluster Vesicle RV/P Cluster Vesicle RV/P
1 NP 2-5 NP 2-5 NP 6-10 NP 6-10 NP > 10 NP > 10 NP
OVA-allergic 22.2 ± 1.4 466 ± 64 20.8 ± 2.5 43.4 ± 2.3 459 ± 53 11.1 ± 1.2 78.7 ± 3.3 401 ± 38 5.1 ± 0.4 156 ± 9 393 ± 25 2.7 ± 0.2
  (n = 16)   (n = 26)   (n = 22)   (n = 38)  
Sham 21.0 ± 0.7 367 ± 38 17.9 ± 1.9 48.6 ± 3.3 338 ± 41 7.7 ± 1.3 83.5 ± 6.5 414 ± 34 5.2 ± 0.5 182 ± 19 393 ± 32 2.4 ± 0.2
  (n = 22)   (n = 28)   (n = 22)   (n = 30)  
Scnn1b-Tg 21.5 ± 0.3 435 ± 30 20.5 ± 1.4 47.9 ± 2.5 393 ± 22 9.4 ± 0.6 74.0 ± 3.3 366 ± 25 5.3 ± 0.4 149 ± 7* 420 ± 19 3.1 ± 0.2
  (n = 69)   (n = 87)   (n = 49)   (n = 77)  
WT 22.5 ± 0.4 543 ± 61 24.5 ± 2.8 50.4 ± 3.3 451 ± 43 10.3 ± 1.1 79.1 ± 3.7 404 ± 33 5.3 ± 0.5 188 ± 9 460 ± 20 2.7 ± 0.2
  (n = 46)   (n = 57)   (n = 34)   (n = 74)  
  1. Data are presented as mean values ± SEM. *Significant difference to control group (P = 0.005); n = number of measurements (vesicle and enclosed AuNP). RV/P = ratio of vesicle to particle diameter.