| Control | IPF | cHP | saHP |
---|
Number of subjects
|
7
|
17
|
5
|
4
|
Age (years)
|
40,2 ± 9,8*
|
62,5 ± 5
|
59,4 ± 8,2
|
53,5 ± 0,7*
|
Male/Female
|
5/2
|
12/5
|
4/1
|
2/2
|
Smoking (no/Ex/C)
|
4/1/2
|
6/9/2
|
2/2/1
|
1/3/0
|
FVC% pred
|
91,8 ± 2,4*
|
63,3 ± 14,2
#
|
73 ± 16,5
|
72 ± 9,9
|
DLCO% pred
|
90,4 ± 3,5*
|
43,7 ± 15
#
|
45,2 ± 18,5
#
|
48,4 ± 17,5
|
%FVC change
| |
- 3,2 ± 6,2
|
- 1,9 ± 3,1
|
- 0,1 ± 2,1*
|
%DLCO change
| |
- 2,9 ± 5,9
|
- 1,1 ± 3,5
|
+ 0,3 ± 4,5*
|
- Data are presented as mean ± SD. Results were analyzed using t-student test for parametric values or Mann–Whitney Rank Sum test for non-parametric values. *p < 0,05: significance difference compared with the IPF group; # p < 0,05: significance difference compared with the control group.
- No: never smoking; Ex: ex-smoker; C: current smoker; FVC: forced vital capacity; DLCO: diffusion lung capacity for carbon monoxide; IPF: idiopathic pulmonary fibrosis; cHP: chronic hypersensitivity pneumonitis; saHP: subacute hypersensitivity pneumonitis. %FVC change: Absolute change in percent-predicted FVC over 24 weeks. %DLCO change: Absolute change in percent-predicted DLCO over 24 weeks.