Skip to main content

Table 1 Characteristics of the study groups

From: Lung fibrotic tenascin-C upregulation is associated with other extracellular matrix proteins and induced by TGFβ1

  Control IPF cHP saHP
Number of subjects 7 17 5 4
Age (years) 40,2 ± 9,8* 62,5 ± 5 59,4 ± 8,2 53,5 ± 0,7*
Male/Female 5/2 12/5 4/1 2/2
Smoking (no/Ex/C) 4/1/2 6/9/2 2/2/1 1/3/0
FVC% pred 91,8 ± 2,4* 63,3 ± 14,2 # 73 ± 16,5 72 ± 9,9
DLCO% pred 90,4 ± 3,5* 43,7 ± 15 # 45,2 ± 18,5 # 48,4 ± 17,5
%FVC change   - 3,2 ± 6,2 - 1,9 ± 3,1 - 0,1 ± 2,1*
%DLCO change   - 2,9 ± 5,9 - 1,1 ± 3,5 + 0,3 ± 4,5*
  1. Data are presented as mean ± SD. Results were analyzed using t-student test for parametric values or Mann–Whitney Rank Sum test for non-parametric values. *p < 0,05: significance difference compared with the IPF group; # p < 0,05: significance difference compared with the control group.
  2. No: never smoking; Ex: ex-smoker; C: current smoker; FVC: forced vital capacity; DLCO: diffusion lung capacity for carbon monoxide; IPF: idiopathic pulmonary fibrosis; cHP: chronic hypersensitivity pneumonitis; saHP: subacute hypersensitivity pneumonitis. %FVC change: Absolute change in percent-predicted FVC over 24 weeks. %DLCO change: Absolute change in percent-predicted DLCO over 24 weeks.