Comparison of the effects of pulmonary rehabilitation with chest physical therapy on the levels of fibrinogen and albumin in patients with lung cancer awaiting lung resection: a randomized clinical trial

Table 1 Baseline characteristics of the participants

Variable	PR (n = 12)	CPT (n = 12)	P
Sex (M/F)*	4/8	5/7	0.46
Age (years)mean ± standard deviation†	65 ± 8	69 ± 7	0.33
BMI (kg · m ^-2 ) mean ± standard deviation	26 ± 5	24 ± 6	0.56
Current smoker (n/%)*	10/83	9/75	0.44
Comorbidity (n/%)*	7/58	4/33	0.35
With COPD (n/%)*	9/75	10/83	0.62
LC stage (n/%)*
Stage I/II	11/92	9/75	0.16
Stage III A	1/8	3/25
Lung function
FEV ₁ (%)mean ± standard deviation†	48 ± 14	49 ± 12	0.41
FVC (%)median(25%-75%)‡	63 (53 – 93)	63 (50 – 71)	0.26
FEV ₁ /FVC (%)median(25%-75%)‡	62 (51 – 73)	56 (53 – 61)	0.71
Arterial blood gas
PaCO₂	41.8 ± 3.8	42.5 ± 3.6	0.3
PaO ₂	75.8 ± 5.8	79.9 ± 1.8	0.2
Fibrinogen (mg/dl) median (25%-75%)‡	414 (366 – 588)	368 (318 – 527)	0.31
Albumin (g/dl) mean ± standard deviation†	4.1 ± 0.6	3.9 ± 0.3	0.35
Physical capacity
UULEX (kg)median (25%-75%)‡	1 (1 – 1.5)	0.75 (0.5 – 1)	0.08
Endurance testing(s) mean ± standard deviation†	429 ± 156	503 ± 216	0.35
6MWT(m) mean ± standard deviation†	425 ± 85	339 ± 108	0.06
Quality of life
SF-36 PCS (%)mean ± standard deviation†	36 ± 8	36 ± 8	0.99
SF-36 MCS (%)mean ± standard deviation†	44 ± 13	43 ± 13	0.86
Anxiety and Depression
*HADS-A* (scores)median (25%-75%)‡	12 (6 – 13)	10 (4 – 14)	0.72
*HADS-D* (scores) mean ± standard deviation†	10 ± 5	10 ± 3	0.75

*Fisher exat test. †student t test ‡Mann–Whitney U test. PR: Pulmonary Rehabilitation group; CPT: Chest Physical Therapy group; M: Male; F: Female; BMI: Body Mass Index; COPD: Chronic Obstructive Pulmonary Disease; LC: Lung Cancer; PaO₂: Partial pressure of Oxygen in arterial blood; PaCO₂: Partial pressure of Carbon Dioxide in arterial blood; FEV₁: Forced Expiratory Volume at the first second; FVC: Forced Vital Capacity; UULEX: unsupported upper limb exercise test; 6MWT: 6-minute Walk Test; PCS: SF-36 Physical Component Summary; MCS: SF-36 Mental Component Summary; HADS-A: Hospital Anxiety and Depression Scale – Anxiety; HADS-D: Hospital Anxiety and Depression Scale – Depression. Student’s t-test was used for continuous variables and Chi-squared test was used for categorical variables.

ISSN: 1471-2466