Table 1 Baseline characteristics of the 171 cases of community-acquired pneumonia included in the study
From: Inflammatory response in mixed viral-bacterial community-acquired pneumonia
Characteristic | Bacterial n = 59 | Viral n = 66 | Mixed n = 46 | p | |
|---|---|---|---|---|---|
Age, years | 72 (14) | 76 (17) | 72 (20) | NS | |
>65 years | 42 (70%) | 50 (75.76%) | 32 (68.09%) | NS | |
Male sex | 42 (70%) | 40 (60.61%) | 23 (48.94%) | NS | |
Smoking status | Yes | 16 (27.12%) | 11 (16.67%) | 9 (19.15%) | NS |
No | 17 (28.81%) | 33 (50%) | 22 (46.81%) | NS | |
Ex-smoker | 26 (44.07%) | 22 (33.33%) | 16 (34.04%) | NS | |
Previous antibiotic | 12 (20%) | 16 (24.24%) | 6 (12.77%) | NS | |
Concomitant illnesses | Neoplastic disease (not active) | 7 (11.67%) | 10 (15.15%) | 5 (10.64%) | NS |
Heart disease | 25 (41.67%) | 23 (34.85%) | 14 (29.79%) | NS | |
Cerebrovascular disease | 11 (18.33%) | 14 (21.21%) | 7 (14.89%) | NS | |
COPD | 21 (35%) | 19 (28.79%) | 12 (25.53%) | NS | |
Liver disease | 2 (3.33%) | 2 (3.03%) | 1 (2.13%) | NS | |
Renal disease | 6 (10%) | 9 (13.64%) | 5 (10.64%) | NS | |
Diabetes mellitus | 11 (18.33%) | 15 (22.73%) | 6 (12.77%) | NS | |
Bronchiectasis | 5 (8.33%) | 1 (1.52%) | 2 (4.26%) | NS | |
No first pneumonia | 20 (33.33%) | 13 (19.7%) | 12 (25.53%) | NS | |
Clinical findings | Duration of symptoms prior to enrolment (mean no. of days) | 3 | 3,75 | 3,25 | NS |
Altered mental status | 5 (8.33%) | 10 (15.15%) | 2 (4.26%) | NS | |
Pulse > 125/min | 9 (15%) | 4 (6.06%) | 2 (4.26%) | NS | |
Respiratory rate > 30/min | 16 (26.67%) | 10 (15.15%) | 5 (10.64%) | NS | |
Systolic BP < 90 mmHg or diastolic BP < 60 mmHg | 11 (18.33%) | 6 (9.09%) | 5 (10.64%) | NS | |
Temperature < 35°C or > 40°C | 3 (5%) | 1 (1.52%) | 2 (4.26%) | NS | |
Radiographic findings | Unilobar involvement | 51 (86.44%) | 58 (89.23%) | 39 (82.98%) | NS |
Multilobar/bilateral involvement | 8 (13.66%) | 8 (10.76%) | 7 (17.02%) | NS | |
Pleural effusion | 15 (25%) | 11 (16.67%) | 12 (25.53%) | NS | |
PSI | Mean PSI score | 101.5 | 106 | 101 | NS |
Class 1-3 | 22 (37.3%) | 23 (34.8%) | 19 (41.3%) | NS | |
Class 2-5 | 37 (62.7%) | 43 (65.2%) | 27 (58.7%) | ||
CURB65 | 0-1 | 23 (39%) | 24 (36.4%) | 19 (41.3%) | NS |
2-5 | 36 (61%) | 42 (63.6%) | 27 (58.7%) | ||
Symptoms | Fever | 45 (77.59%) | 46 (71.88%) | 35 (76.09%) | NS |
Cough | 44 (73.33%) | 53 (79.1%) | 39 (82.98%) | NS | |
Expectoration | 40 (67.8%) | 47 (73.44%) | 35 (77.78%) | NS | |
Dyspnea | 39 (67.24%) | 48 (73.85%) | 31 (67.39%) | NS | |
Pleuritic pain | 27 (46.55%) | 23 (37.1%) | 28 (63.64%) | 0.026 | |
Digestive | 9 (15.52%) | 8 (12.9%) | 12 (26.09%) | NS | |
Headache | 5 (20%) | 7 (22.58%) | 8 (42.11%) | NS | |
Myalgia | 4 (16.67%) | 8 (27.59%) | 7 (36.84%) | NS |