Evidence of mycobacterial disease in COPD patients with lung volume reduction surgery; the importance of histological assessment of specimens: a cohort study

Table 3 Comparison of selected variables between patients with and without evidence of mycobacterium infection

Age, BMI, Exacerbations/Year and Pre-Operative Lung Function of patients without mycobacterium evidence compared to those with mycobacterium evidence (Mean ± SD)
	No Mycobacterium	Mycobacterium	P value 95% CI
No. of patients	112	14
Male: Female ratio	89:23	9:5	0.303
Age, years	57.5 ± 10.39	63.0 ± 6.02	0.054
Age, years	57.5 ± 10.39	63.0 ± 6.02	(95% CI: −0.096-11.15)
BMI	23.9 ± 4.04	22.1 ± 4.36	0.110
BMI	23.9 ± 4.04	22.1 ± 4.36	(95% CI: −4.15-0.42)
Exacerbations/Year	2.2 ± 2.40	5.3 ± 2.69	<0.001
Exacerbations/Year	2.2 ± 2.40	5.3 ± 2.69	(Mann–Whitney Test, 95% CI not possible)
FEV ₁ , % predicted	37.7 ± 17.17	25.0 ± 6.58	<0.001
FEV ₁ , % predicted	37.7 ± 17.17	25.0 ± 6.58	(95% CI: −17.55 -7.84)
FVC, % predicted	81.7 ± 21.44	74.1 ± 15.00	0.207
FVC, % predicted	81.7 ± 21.44	74.1 ± 15.00	(95% CI: −19.23-4.20)
TLCO, % predicted	42.6 ± 17.88	30.7 ± 9.11	<0.001
TLCO, % predicted	42.6 ± 17.88	30.7 ± 9.11	(95% CI: −18.05-- 5.85)
RV, % predicted	218.1 ± 59.20	215.6 ± 63.17	0.881
RV, % predicted	218.1 ± 59.20	215.6 ± 63.17	(95% CI: −36.11-31.02)
TLC, % predicted	127.8 ± 21.49	130.0 ± 23.10	0.722
TLC, % predicted	127.8 ± 21.49	130.0 ± 23.10	(95% CI: −9.99- 14.39)

Data shown as mean ± SD. FEV₁: Forced expiratory volume in 1 sec; FVC: Forced vital capacity; TLCO: Transfer factor of the lung for carbon monoxide; RV: Residual volume; TLC: Total lung capacity. These variables are all shown as percentage predicted.

ISSN: 1471-2466