Table 1 Characteristics of patients hospitalized with pneumonia by Streptococcus pneumoniae by blood culture result

 Age, years, mean (SD)

 Age ≥65 years

 Age >75 years

 Women

 Underlying diseases

  Cancer

  Liver disease

  Congestive heart failure

  Cerebrovascular disease

  Renal disease

  Chronic obstructive pulmonary disease

  Diabetes mellitus

 Number of comorbid conditions

  0

  1

  ≥2

 Nursing home resident

 Smoking

  No

  Yes

  Ex-smoker

 Alcoholism

 Influenza vaccine in the last year

 Pneumococcal vaccine in the last 5 years

Findings on physical examination on admission

 Altered mental status

 Pulse ≥ 125/min

 Respiratory rate ≥ 30/min

 Systolic blood pressure < 90 mmHg

 Temperature < 35°C or ≥ 40°C

Laboratory findings on admission

 Blood urea nitrogen > 30 mg/dL

 Glucose ≥ 250 mg/dL

 Hematocrit < 30%

 Sodium < 130 mmol/L

 PaO₂ < 60 mmHg

 Arterial pH < 7.35

Radiological findings on admission

 Bilateral or multilobe radiological involvement

 Pleural effusion

Severity of illness on admission

CURB65 score^*

 0,1

 2

 >2