Skip to main content

Table 1 Characteristics of patients hospitalized with pneumonia by Streptococcus pneumoniae by blood culture result

From: Pneumococcal pneumonia: differences according to blood culture results

Characteristics Blood culture positive (N = 399) Blood culture negative (N = 492) Pvalue
 Age, years, mean (SD) 63.6 (18.5) 65.2 (17) 0.2
 Age ≥65 years 225 (56.4) 290 (58.9) 0.4
 Age >75 years 130 (32.6) 167 (33.9) 0.7
 Women 131 (32.8) 210 (42.7) 0.003
 Underlying diseases    
  Cancer 27 (6.8) 17 (3.5) 0.2
  Liver disease 18 (4.5) 12 (2.4) 0.1
  Congestive heart failure 54 (13.5) 43 (8.7) 0.02
  Cerebrovascular disease 22 (5.5) 32 (6.5) 0.5
  Renal disease 27 (6.8) 24 (4.9) 0.2
  Chronic obstructive pulmonary disease 74 (18.6) 116 (23.6) 0.07
  Diabetes mellitus 60 (15.1) 97 (19.8) 0.07
 Number of comorbid conditions    0.96
  0 203 (50.9) 253 (51.4)  
  1 130 (32.6) 156 (31.7)  
  ≥2 66 (16.5) 83 (16.9)  
 Nursing home resident 13 (3.3) 20 (4.1) 0.5
 Smoking    0.06
  No 130 (43.5) 225 (47.8)  
  Yes 86 (28.8) 100 (21.2)  
  Ex-smoker 83 (27.8) 146 (31)  
 Alcoholism 58 (15.3) 44 (9.4) 0.008
 Influenza vaccine in the last year 93 (26.4) 149 (30.9) 0.2
 Pneumococcal vaccine in the last 5 years 14 (3.8) 121 (25.5) <0.0001
Findings on physical examination on admission    
 Altered mental status 39 (9.8) 49 (10) 0.9
 Pulse ≥ 125/min 62 (15.6) 62 (12.6) 0.2
 Respiratory rate ≥ 30/min 98 (24.8) 96 (19.5) 0.06
 Systolic blood pressure < 90 mmHg 30 (7.5) 42 (8.5) 0.6
 Temperature < 35°C or ≥ 40°C 7 (1.8) 4 (0.8) 0.2
Laboratory findings on admission    
 Blood urea nitrogen > 30 mg/dL 192 (48.1) 163 (33.1) <0.0001
 Glucose ≥ 250 mg/dL 39 (9.8) 38 (7.7) 0.3
 Hematocrit < 30% 10 (2.5) 23 (4.7) 0.1
 Sodium < 130 mmol/L 33 (8.3) 22 (4.5) 0.02
 PaO2 < 60 mmHg 188 (47.1) 209 (42.5) 0.2
 Arterial pH < 7.35 31 (7.8) 24 (4.9) 0.07
Radiological findings on admission    
 Bilateral or multilobe radiological involvement 142 (35.7) 122 (24.8) 0.0004
 Pleural effusion 65 (16.3) 43 (8.7) 0.0006
Severity of illness on admission    
CURB65 score*    0.07
 0,1 145 (36.3) 215 (43.7)  
 2 159 (39.9) 167 (33.9)  
 >2 95 (23.8) 110 (22.4)  
  1. SD, standard deviation.
  2. Data are expressed as numbers (percentage) unless otherwise stated. Percentages exclude patients with missing data.
  3. *Severity of illness on admission assessed with CURB-65 (Confusion, Urea nitrogen, Respiratory rate, Blood pressure, age ≥65 years) score.