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Table 2 Process-of-care of patients hospitalized with pneumonia by Streptococcus pneumoniae by blood culture result

From: Pneumococcal pneumonia: differences according to blood culture results

Process-of-care Blood culture positive (N = 399) Blood culture negative (N = 492) Pvalue
Previous antibiotic treatment 26 (6.5) 56 (11.4) 0.013
Appropriate antibiotic* 273 (68.6) 419 (85.3) <0.0001
Antibiotics within 4 hours 257 (73) 389 (79.7) 0.019
Antibiotics within 8 hours 330 (93.8) 471 (96.5) 0.06
Length of antibiotic therapy, days, mean (SD) 14.7 (7.2) 13.9 (4.6) 0.9
Length of intravenous antibiotic therapy, days, mean (SD) 7 (7.2) 5.9 (4.8) 0.4
Antibiotic treatment    <0.0001
  Beta-lactam monotherapy 93 (23.4) 113 (23)  
  Beta-lactam/macrolide 13 (3.3) 30 (6.1)  
  Fluoroquinolones 257 (64.6) 346 (70.5)  
  Macrolide monotherapy 1 (0.3) 0 (0)  
  Others 34 (8.5) 2 (0.4)  
Dual antibiotic therapy including a macrolide 13 (3.3) 31 (6.3) 0.037
  1. SD, standard deviation.
  2. Data are given as number (percentage) unless otherwise indicated. The percentage excluded patients with missing data.
  3. *Appropriate antibiotic defined as usage of antibiotics recommended in the guidelines of the SEPAR.
  4. Deaths are excluded.