Table 2 Process-of-care of patients hospitalized with pneumonia by Streptococcus pneumoniae by blood culture result
From: Pneumococcal pneumonia: differences according to blood culture results
Process-of-care | Blood culture positive (N = 399) | Blood culture negative (N = 492) | Pvalue |
|---|---|---|---|
Previous antibiotic treatment | 26 (6.5) | 56 (11.4) | 0.013 |
Appropriate antibiotic* | 273 (68.6) | 419 (85.3) | <0.0001 |
Antibiotics within 4 hours | 257 (73) | 389 (79.7) | 0.019 |
Antibiotics within 8 hours | 330 (93.8) | 471 (96.5) | 0.06 |
Length of antibiotic therapy, days, mean (SD)† | 14.7 (7.2) | 13.9 (4.6) | 0.9 |
Length of intravenous antibiotic therapy, days, mean (SD)† | 7 (7.2) | 5.9 (4.8) | 0.4 |
Antibiotic treatment | <0.0001 | ||
Beta-lactam monotherapy | 93 (23.4) | 113 (23) | |
Beta-lactam/macrolide | 13 (3.3) | 30 (6.1) | |
Fluoroquinolones | 257 (64.6) | 346 (70.5) | |
Macrolide monotherapy | 1 (0.3) | 0 (0) | |
Others | 34 (8.5) | 2 (0.4) | |
Dual antibiotic therapy including a macrolide | 13 (3.3) | 31 (6.3) | 0.037 |