From: Pneumococcal pneumonia: differences according to blood culture results
In-hospital evolution and outcomes | Positive blood culture (N = 399) | Negative blood culture (N = 492) | Pvalue | Odds ratio (95% CI) |
---|---|---|---|---|
In-hospital course | ||||
Admission to intensive care unit | 92 (23.1) | 101 (20.5) | 0.4 | 1.2 (0.8 – 1.6) |
Need for mechanical ventilation | 42 (10.5) | 27 (5.5) | 0.005 | 2 (1.2 – 3.4) |
Septic shock* | 53 (14.9) | 33 (6.7) | 0.0001 | 2.4 (1.5 – 3.8) |
Treatment failure | 72 (18.2) | 59 (12.1) | 0.01 | 1.6 (1.1 – 2.3) |
Severe sepsis | 185 (46.4) | 203 (41.3) | 0.1 | 1.2 (0.9 – 1.6) |
Outcomes | ||||
In-hospital mortality | 35 (8.8) | 22 (4.5) | 0.009 | 2.1 (1.2 – 3.6) |
15-day mortality | 33 (8.3) | 14 (2.9) | 0.0003 | 3.1 (1.6 – 5.8) |
30-day mortality | 37 (9.3) | 18 (3.7) | 0.0005 | 2.7 (1.5 – 4.8) |
30-day readmission | 10 (3.3) | 27 (5.6) | 0.1 | 0.6 (0.3 – 1.2) |
Length of hospital stay (days)† | ||||
Mean (SD) | 10 (13.7) | 7 (5.5) | 0.02 | 1.2 (1.04 – 1.3)║ |
Median (IRQ) | 6 (4 – 10) | 6 (4 – 8) | 0.02 | |
>3 days | 295 (81) | 373 (79.4) | 0.5 | 1.1 (0.8 – 1.6) |