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Table 1 Summary of post-transplantation survival among patients with IPF

From: Lung transplantation in idiopathic pulmonary fibrosis: a systematic review of the literature

Data source Yr. of transplant No. of IPF patients % of patients alive (95% confidence interval)
3 mo. 1 yr. 3 yr. 5 yr. 10 yr.
ISHLT data
ISHLT website & ISHLT 2012 Annual Report [12, 18] 1990 – 2011 8,528 85 75 59 47 24
OPTN data
OPTN website [19] 1997 – 2004a 1,271b NR 80 (77, 83) 57 (53, 61) 41 (36, 44) NR
2011 Annual Report [11] 2005 – 2006 755 91 81 64 53 NR
Analysis of OPTN data (Meyer, et al) [20] 1988 – 1997 NR NR NR NR 32.1 ± 2.4% (mean±SE) NR
Analysis of OPTN data (Thabut, et al) [21] 1987 – 2009 3,327 NR 76 (75, 78) 59 (57, 61) 44 (42, 46) NR
Analysis of OPTN data (Edwards, et al)[22] 1996 – 2001 786 NR ~68c ~50c ~39c NR
Analysis of OPTN data (McCurry, et al) [23] 2001 – 2006 1,636 NR NR NR 49 NR
Analysis of OPTN data (Chen, et al) [24] 2002 – 2005 1,418 NR ~79 (~75, ~82)c NR NR NR
2005 – 2008 1,563 NR ~80 (~78, ~83)c NR NR NR
Analysis of OPTN data (Freitas, et al) [25] 1987 – 2009 4,205 NR 77d 58d 44d NR
OPTN and Loyola University Medical Center databases [26] 1991 – 2009 4,190 NR 78 61 47 NR
Other registries and large databases
Spanish Lung Transplant Registry (Coll, et al) [27] 2006 – 2010 261 ~80c ~63c NR NR NR
Nationwide Inpatient Sample, US (Teo, et al) [28] 1988 – 2006 231 In-hospital: 91 NR NR NR NR
Single center studies in Europe, Brazil and Australia
Single center in Denmark (Burton, et al) [29] 1992 – 2004 21 76 NR 52 NR  
Inova Fairfax Hospital Interstitial Lung Disease Clinic, England (Nathan, et al) [30, 31] 2000 – 2009 84 NR 83 61 41 NR
1996 – 2002 23 95.7 NR NR NR NR
Papworth Hospital, England (McNeil, et al) [32] 1984 – 1994 11 46 NR NR NR NR
Hopital Beaujon, France (Thabut, et al) [33] 1988 – 2001 28 30 day: 93 79 2 yr: 64 39 NR
University of Munich, Germany (Neurohr, et al) [34] 1997 – 2008 76 87 74 65 53 7.5 yrs: 40
University of Cordoba, Spain (Algar, et al) [35] 1993 – 2009 89 NR 53 40 33  
Santa Casa de Misericordia de Porto Alegre, Brazil (Machuca, et al) [36] 2004 – 2009 53 NR 72 NR NR NR
Alfred Hospital, Melbourne, Australia (Keating, et al) [37] 1990 – 2008 67 NR 76 NR 50 34
Single center studies in North America
University of Pittsburgh, US (DiGiuseppe, et al) [38] 1986 – 2007 78   NR NR 50 ~32c
Two centers (Johns Hopkins Hospital and the University of Pittsburgh Medical Center), US (Schachna, et al) [39] 1989 – 2002 70 6-month: 80 2-year: 67 NR NR NR
University of Pennsylvania, US (Rivera-Lebron, et al) [40] 2005 – 2010 68 NR 78 NR 52 NR
Washington University School of Medicine, St Louis, Mo, US (Meyers, et al) [41] 1988 –1998 45 NR 76 NR 54 NR
University of California, Los Angeles, US (Saggar, et al) [42] 2003 – 2007 38 NR 87 NR NR NR
Vanderbilt University Medical Center, US (Milstone, et al) [43] 1990 – 1998 32 NR 25 NR NR NR
University of Virginia, US (Smith, et al) [44] 1995 – 2005 27 30 day: <60 yrs: 100; ≥60 yrs: 93 (79, 100) <60 yrs: 85 (65, 100) ≥ 60 yrs: 93 (79, 100) <60 yrs: 68 (42, 94) ≥ 60 yrs: 93 (79, 100) <60 yrs: 48 (19, 78) ≥60 yrs: 58 (26, 90) NR
University of Alabama, US (Wille, et al) [45] 1994 – 2004 48 87 80 67 47 NR
Washington University/Barnes Hospital (Davis, et al) [46] 1998 – 1993 16 In-hospital: 87 72 62 NR NR
Toronto Lung Transplant Group, Canada (Grossman, et al) [47] 1983 – 1989 16 NR 63 NR NR NR
Cleveland Clinic, US (Mason, et al) [48] 1990 – 2005 82 30-day: 95 73 56 44 7-year: 36
University of Wisconsin Hospital and Clinics (De Oliviera, et al) [49, 50] 1993 – 2009 79 In-hospital: 94 82 63 63 NR
  1. a 1-year survival based on 2002 – 2004 transplants, 3-year survival based on 1999 – 2002 transplants, 5-year survival based on 1997 – 2000 transplants.
  2. b Denominator gotten from http://optn.transplant.hrsa.gov/latestData/rptData.asp.
  3. c Percent is estimated based on graphical display of data.
  4. d Graft survival.