A symptom-related monitoring program following pulmonary embolism for the early detection of CTEPH: a prospective observational registry study

Table 2 Results of telephone monitoring and administration of 5-item-questionnaire, echocardiography, cardiopulmonary exercise testing and further evaluation confirming CTEPH

	Visit 1, 3 months	Visit 2, 6 months	Visit 3, 12 months
	N(%)	N(%)	N(%)
Telephone calls	130	102	58
5-Item-Questionnaire positiv	49 (37.7%)	26 (25.5%)	17 (29,3%)
Outpatient visits	49	26	17
Echocardiography,	n = 49	n = 26	n = 16
RVSP >/=35 mm Hg	10 (20.4%)	3 (11.5%)	3 (18.8%)
REVSP < 35 mm Hg/ not detectable	39 (79.6%)	23 (88.5%)	13 (81.25%)
Cardiopulmonary exercise testing,	n = 34	n = 15	n = 9
Abnormal pulmonary perfusion suspected	12 (35.28%)	4 (26.7%)	1 (11.1%)
Further evaluation	21	7	4
CTEPH/CTPVD proven per visit	5(3.85)/2(1.5%)	3(2.94/1(0.98%)	0/0.0%)
CTEPH/CTPVD proven, all patients	5(3.85%)/2(1.5%)	8(6.2%)/3(2.3%)	8(6.2%)/3(2.3%)

26 months after the start of the program 130 patients had passed 3-months follow-up, 102 patients had completed 6 months follow-up and 58 patients had passed twelve months-follow-up.