Non specific pattern of lung function in a respiratory physiology unit: causes and prevalence: results of an observational cross-sectional and longitudinal study

Table 2 Main characteristics of the patients with NSP according to underlying condition

Characteristic	Asthma	COPD/emphysema	Bronchiectasis	Sarcoidosis	Interstitial pneumonia	Pulmonary hypertension	Bilateral lung transplantation	Pvalue
Mean ± SD (except when stated) or n	Asthma	COPD/emphysema	Bronchiectasis	Sarcoidosis	Interstitial pneumonia	Pulmonary hypertension	Bilateral lung transplantation	Pvalue
Mean ± SD (except when stated) or n	N = 67	N = 55	N = 14	N = 12	N = 15	N = 7	N = 15
Sex, F/M	48/19	17/38	12/2	7/5	6/9	5/2	4/11	<0.0001
Age, years	51 ± 15	64 ± 10	60 ± 16	47 ± 15	66 ± 14	47 ± 17	28 ± 9	<0.0001
BMI, kg.m⁻²	30.6 ± 9.3	26.7 ± 6.2	21.1 ± 2.4	27.3 ± 5.3	28.1 ± 5.9	22.4 ± 4.6	17.7 ± 1.6	<0.0001
Smoking history								<0.0001
Never smokers, n	54	0	11	9	10	6	15
Ex-smokers, n	6	31	2	3	5	1	0
Current smokers, n	7	24	1	0	0	0	0
Pack-year, median [IQ]	0 [0 – 0]	45 [36 – 59]	0 [0 – 0]	0 [0 – 4]	0 [0 – 3]	0 [0 – 0]	0 [0 – 0]	<0.0001
MRC score, median [IQ]	2 [1 – 2]	2 [1 – 2]	1 [1 – 2]	2 [2 – 2]	2 [2 – 2]	2 [1 – 5]	1 [1 – 1]	0.0003
FEV₁,% predicted	64 ± 7	63 ± 8	61 ± 9	67 ± 8	69 ± 8	59 ± 5	66 ± 8	0.118
FVC,% predicted	65 ± 8	65 ± 9	63 ± 9	70 ± 10	68 ± 9	63 ± 5	66 ± 9	0.239
FEV₁/FVC,% predicted	97 ± 8	96 ± 7	96 ± 7	95 ± 6	99 ± 10	93 ± 5	100 ± 8	0.321
TLC,% predicted	94 ± 10	99 ± 14	96 ± 8	90 ± 7	90 ± 9	96 ± 15	93 ± 6	0.189
FRC,% predicted	102 ± 27	121 ± 26	116 ± 21	97 ± 14	96 ± 16	111 ± 35	127 ± 11	<0.0001
RV,% predicted	132 ± 33	145 ± 33	136 ± 22	119 ± 21	110 ± 25	136 ± 30	169 ± 28	<0.0001

ISSN: 1471-2466