Intravenous insulin therapy during lung resection does not affect lung function or surfactant proteins

BMC Pulmonary Medicine

Table 6 Changes between the initial examination and the examination 2 hours after the surgery in insulin-treated diabetic and non-diabetic patients

Insulin treated N = 31	Mean change	SD	Median change	Min	Max	P
pH	0.03	0.06	0.03	-0.10	0.17	0.008
pCO₂	-0.80	0.76	-0.80	-2.40	0.80	<0.001
pO₂	-12.52	9.53	-9.70	-37.20	3.50	<0.001
HCO_3-	-1.59	1.98	-1.70	-5.30	2.50	<0.001
HCO_3- std	-0.77	1.73	-0.90	-4.40	2.10	0.019
BE	-1.11	1.92	-1.40	-5.90	2.90	0.003
Non-diabetes N = 20	Mean change	SD	Median change	Min	Max	p
pH	0.03	0.06	0.03	-0.10	0.13	0.030
pCO₂	-0.90	0.70	-0.95	-2.10	0.10	<0.001
pO₂	-12.64	7.92	-11.75	-29.20	2.80	<0.001
HCO_3-	-1.77	2.05	-2.00	-4.70	2.50	0.001
HCO_3- std	-0.92	1.70	-1.05	-4.40	2.10	0.026
BE	-1.36	2.04	-1.30	-5.90	2.90	0.008
Diabetes N = 11	Mean change	SD	Median change	Min	Max	p
pH	0.03	0.07	0.02	-0.07	0.17	0.148
pCO₂	-0.63	0.86	-0.70	-2.40	0.80	0.036
pO₂	-12.30	12.37	-9.10	-37.20	3.50	0.008
HCO_3-	-1.25	1.90	-1.20	-5.30	0.90	0.054
HCO_3- std	-0.51	1.83	-0.70	-4.10	1.80	0.379
BE	-0.66	1.67	-1.40	-3.40	2.00	0.218

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