Intestinal current measurement versus nasal potential difference measurements for diagnosis of cystic fibrosis: a case–control study

Table 2 Influence of smoking (active and/or passive) in healthy controls on NPD and ICM CFTR responses

	Nonsmokers	Smokers	*p-value*
	n = 5	n = 8	*p-value*
Sweat chloride (mmol/L)	18 ± 8	20 ± 9	NS
NPD CFTR response	-19.3 ± 7.4	-10.1 ± 7.3	0.049
Average Δ0Cl^- + Iso (mV)
ICM CFTR response	97.2 ± 37.1	65.7 ± 29.1	NS
Average ΔIsc (μA/cm²)
(forskolin/IBMX + carbachol + histamine)

ISSN: 1471-2466