Table 2 Effect of indacaterol and tiotropium versus placebo on lung function

ITGV

Peak

-0.41 L p < 0.001; 95% CI: -0.54– -0.29

-0.38 L p < 0.001; 95% CI: -0.51– -0.25

Trough

-0.27 L p < 0.001; 95% CI: -0.40– -0.14

-0.21 L p = 0.002; 95% CI: -0.35– -0.08

RV

Peak

-0.40 L p < 0.001; 95% CI: -0.54– -0.25

-0.39 L p < 0.001; 95% CI: -0.53– -0.25

Trough

-0.32 L p = 0.001; 95% CI: -0.48– -0.15

-0.25 L p = 0.003; 95% CI: -0.42– -0.09

TLC

Peak

-0.16 L p = 0.021; 95% CI: -0.30– -0.03

-0.20 L p = 0.006; 95% CI: -0.34– -0.06

Trough

-0.08 L p = 0.320; 95% CI: -0.23–0.07

-0.11 L p = 0.170; 95% CI: -0.26–0.05

IRV

Peak

0.12 L p = 0.003; 95% CI: 0.04–0.19

0.08 L p = 0.049; 95% CI: 0.00–0.15

Trough

0.17 L p < 0.001; 95% CI: 0.09–0.25

0.11 L p = 0.005; 95% CI: 0.03–0.19

sRaw

Peak

-1.02 kPa*sec p < 0.001; 95% CI: -1.23– -0.81

-1.08 kPa*sec p < 0.001; 95% CI: -1.29– -0.87

Trough

-0.81 kPa*sec p < 0.001; 95% CI: -1.00– -0.62

-0.63 kPa*sec p < 0.001; 95% CI: -0.83– -0.44

FEV₁

Peak

0.24 L p < 0.001; 95% CI: 0.20–0.28

0.24 L p < 0.001; 95% CI: 0.19–0.28

Trough

0.19 L p < 0.001; 95% CI: 0.15–0.24

0.17 L p = 0.001; 95% CI: 0.13–0.22