Table 1 Study sample demographics and clinical outcomes
From: Self-reported exercise and longitudinal outcomes in cystic fibrosis: a retrospective cohort study
Mean ± S.D. [range] | Entire study sample | No exercise | Any exercise | Pvalue |
|---|---|---|---|---|
n | 1038 | 264 | 774 | - |
Sex (% male) | 51.8 | 47.0 | 53.5 | 0.07 |
Race/Ethnicity (% non-white) | 9.2 | 11.0 | 8.5 | 0.23 |
(n = 1036) | (n = 263) | (n = 773) | ||
Age at Diagnosis (years) | 2.5 ± 5.7 | 1.5 ± 4.7 | 2.8 ± 6.0 | 0.002 |
[0, 52] | [0, 51] | [0, 52] | ||
(n = 1025) | (n = 259) | (n = 766) | ||
CFTR Genotype (% F508del homozygotes) | 45.2 | 46.4 | 44.7 | 0.64 |
(n = 1023) | (n = 263) | (n = 760) | ||
Exocrine Pancreatic Function (% insufficient) | 83.3 | 85.9 | 82.4 | 0.19 |
(n = 1017) | (n =256) | (n = 761) | ||
Age at Ascertainment of Exercise Status (years) | 13.8 ± 10.2 | 10.1 ± 11.1 | 15.0 ± 9.6 | <0.001 |
[0.1, 61.3] | [0.1, 61.3] | [1.4, 57.8] | ||
Wheezing Reported with Exercise (% yes) | 23.4 | 22.0 | 23.9 | 0.54 |
(n = 995) | (n = 250) | (n = 745) | ||
Baseline FEV 1 % Predicted † | 84.5 ± 22.5 | 78.0 ± 26.7 | 85.6 ± 21.5 | 0.001 |
[19.7, 145.8] | [19.7, 145.8] | [21.4, 137.6] | ||
(n = 766) | (n = 115) | (n = 651) | ||
Change in FEV 1 % Predicted/Year †† | -1.33 ± 4.65 | -0.99 ± 5.48 | -1.39 ± 4.47 | 0.44 |
[-26.4, 24.3] | [-26.4, 23.4] | [-23.2, 24.3] | ||
(n = 558) | (n = 94) | (n = 464) | ||
Baseline BMI Z-score † | -0.15 ± 0.99 | -0.12 ± 1.05 | -0.16 ± 0.98 | 0.55 |
[-4.72, 3.12] | [-4.06, 3.12] | [-4.72, 2.50] | ||
(n = 904) | (n = 207) | (n = 697) | ||
Change in BMI Z-score/Year †† | -0.01 ± 0.20 | 0.02 ± 0.23 | -0.01 ± 0.19 | 0.16 |
[-1.02, 0.83] | [-1.02, 0.70] | [-0.82, 0.83] | ||
(n = 591) | (n = 134) | (n = 457) |