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Table 1 Characteristics of participants

From: Oxygen kinetics during 6-minute walk tests in patients with cardiovascular and pulmonary disease

  Healthy COPD Restrictive PAH CHF
n 16 84 39 54 27
Sex (females) 8 40 21 36 12
Age (years) 37 ± 12 62 ± 14 63 ± 11 61 ± 14 70 ± 9
BMI (kg/m2) 24 ± 4 26 ± 6 30 ± 7 28 ± 6 31 ± 8
FEV1(l/s) 3.9 ± 0.9 1.3 ± 0.5 1.8 ± 0.6 1.9 ± 0.7 (n = 53) 2.4 ± 0.8
FVC (l) 5.0 ± 1.3 (n = 15) 2.6 ± 0.8 2.3 ± 0.8 2.8 ± 1.0 (n = 53) 3.3 ± 1.2
FEV1/FVC 0.8 ± 0.1 (n = 15) 0.5 ± 0.1 (n = 82) 0.8 ± 0.1 0.7 ± 0.2 (n = 53) 0.7 ± 0.1
VO2SS (ml/min) 2376 ± 630 1031 ± 264 1144 ± 299 961 ± 263 1184 ± 342
VO2MAX (ml/min) 2377 ± 630 1012 ± 272 1156 ± 289 945 ± 261 1191 ± 331
VO2MAX (% predicted) 96 ± 15 60 ± 17 66 ± 19 58 ± 18 66 ± 14
HRmax (%predicted) 86 ± 10 69 ± 13 71 ± 12 73 ± 16 70 ± 13
Walking distance (m) 720 ± 83 357 ± 110 381 ± 111 339 ± 120 341 ± 91
Borg 4.1 ± 2.4 4.8 ± 2.4 (n = 80) 4.7 ± 2.1 4.9 ± 2.6 4.5 ± 2.5
Follow-up time (months) 38 ± 6 16 ± 13 21 ± 16 16 ± 14 14 ± 12
Death (n) 0 4 3 10 0
Hospitalizations during follow-up 0 34 17 27 14
MRT (min) 1.13 ± 0.28 1.06 ± 0.28 1.08 ± 0.32 1.07 ± 0.30 0.92 ± 0.34
wMRT (min2/ml) 0.66 × 10-3 ± 0.13 2.18 × 10-3 ± 1.68 1.72 × 10-3 ± 0.81 2.59 × 10-3 ± 1.18 1.62 × 10-3 ± 0.55
  1. Data are presented as mean (SD). BMI: body mass index; FEV1: forced expiratory volume in one second; FVC; forced expiratory vital capacity: FEV1/ FVC ratio: forced expiratory volume in 1 sec (FEV1) expressed as % of FVC; VO2SS = oxygen uptake at steady state; VO2MAX = maximum oxygen uptake; HRmax: maximum heart rate: MRT: mean response time; wMRT: mean response time corrected for work rate.
  2. The participants are grouped into 5 categories: healthy controls (Healthy); restrictive lung disease (Restrictive); chronic obstructive pulmonary disease (COPD); pulmonary arterial hypertension (PAH); congestive heart failure (CHF).