From: Noninvasive ventilation reduces energy expenditure in amyotrophic lateral sclerosis
Parameters | Median [1st-3rdquartiles] |
---|---|
Anthropometric data | |
Age (years) | 68 [56.5-73] |
Gender (male/female) | 12/4 |
BMI (kg/m2) | 21.4 [19.1-26.6] |
Smoking (yes/no) | 10/6 |
Neurological assessment | |
ALS-FRS-R score | 31 [26.5-35] |
Norris bulbar score | 35 [26.2-38] |
Respiratory assessment | |
Dyspnea score on MMRC scale | 3 [1-3.5] |
Inspiratory contraction of inspiratory neck muscles during quiet breathing in supine position (yes/no) | 16/0 |
Inspiratory contraction of inspiratory neck muscles during indirect calorimetry in sitting position (yes/no) | 11/5 |
PaCO2 (mmHg) | 45 [42.5-48] |
PaO2 (mmHg) | 73 [66.5-77.5] |
Bicarbonate (mmol/l) | 28 [27-29.5] |
Time spent with SpO2 < 90% (% of recording time) | 30 [6.2-72] |
FVC sitting (ml) | 1990 [1140-2045] |
FVC sitting (% predicted) | 47 [35-54] |
FVC supine (ml) | 1650 [847-2182] |
FVC supine (% predicted) | 38.5 [30-58] |
PiMAX (cmH2O) | 31 [19.7-58.2] |
PiMAX (% predicted) | 37 [19.5-55.2] |
SNIP (cmH2O) | 32 [16.5-40.2] |
SNIP (% predicted) | 39 [23.2-42.7] |