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Table 1 IC 50 values for cisplatin in NSCLC cell lines with or without GC7 treatment

From: Cisplatin sensitivity is enhanced in non-small cell lung cancer cells by regulating epithelial-mesenchymal transition through inhibition of eukaryotic translation initiation factor 5A2

NSCLC cell line

IC50(μg/mL)▲

 

Cisplatin

Cisplatin + GC7 (20 μM)

A549

3.069 (2.735–3.402)

2.360 (2.098–2.622)**

NCI-H1299

7.140 (6.432–7.848)

4.454 (3.848–5.060)****

  1. ▲IC50 concentrations of cisplatin [μg/mL; mean (95% CI)].
  2. ** P <0.05 vs. cisplatin alone.
  3. **** P <0.0001 vs. cisplatin alone.
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BMC Pulmonary Medicine

ISSN: 1471-2466

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