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Table 2 Comparison of clinical features among three groups

From: Nonspecific interstitial pneumonia: clinical associations and outcomes

 

SAD-NSIP

i-NSIP-Ab+

i-NSIP-Ab-

P

 

N (%)

N (%)

N (%)

 

Cough, initial presentation

14/23(60.9)

21/30(70.0)

22/44(50.0)

0.150

 After follow up

17/28(60.7)

21/31(67.7)

19/38(50.0)

0.215

Dyspnea, initial presentation

13/23(56.5)

21/30(70.0)

34/44(77.3)

0.334

 After follow up

17/28(60.7)

22/31(71.0)

29/38(76.3)

0.389

Fever, initial presentation

5/23(21.7)

10/30(33.3)

10/44(22.7)

0.475

 After follow up

9/28(36.0)

9/31(29.0)

7/38(18.4)

0.399

Weight loss, initial presentation

1/23(4.3)

7/30(23.3)

8/44(18.2)

0.168

 After follow up

3/28(10.7)

8/31(25.8)

5/38(13.2)

0.230

Arthralgia, initial presentation

5/23(21.7)

5/30(16.7)

6/44(13.6)

0.697

 After follow up

7/28(25.0)

6/31(19.4)

3/38(7.9)

0.158

Raynaud’s phenomenon, initial presentation

3/23(13.0)

3/30(10)

0

0.063

 After follow up

3/28(10.7)

3/31(9.7)

0

0.126

Dry eyes or dry mouth, initial presentation

3/23(13.0)

1/30(3.3)

3(6.8)

0.396

 After follow up

3/28(10.7)

1/31(3.2)

3(6.5)

0.529

Oral ulcer, initial presentation

4/23(17.4)

2/30(6.7)

1/44(2.3)

0.075

 After follow up

4/28(14.3)

2/31(6.5)

1/38(2.6)

0.191

Skin rash, initial presentation

8/23(34.8)

12/30(40.0)

1/44(2.3)

0.000*

 After follow up

8/28(28.6)

13/31(41.9)

0

0.000*

Proximal muscle weakness, initial presentation

3/23(13.0)

0

2/44(4.5)

0.101

 After follow up

3/28(10.7)

0

2/38(5.3)

0.178

Morning stiffness, initial presentation

2/23(10.7)

0

0

0.037**

 After follow up

2/28(7.1)

0

0

0.081

Gastroesophageal reflux, initial presentation

2/23(8.7)

0

0

0.037**

 After follow up

2/28(7.1)

0

0

0.081

Photosensitivity, initial presentation

0

0

1/44(2.3)

0.544

 After follow up

0

0

1/38(2.6)

0.456

Crackles, initial presentation

17/23(73.9)

16/30(53.3)

28/44(63.6)

0.173

 After follow up

18/28(64.3)

16/31(51.6)

27/38(71.0)

0.343

Clubbing, initial presentation

2/23(8.7)

3/30(10.0)

1/44(2.3)

0.339

 After follow up

2/28(7.1)

3/31(9.7)

1/38(2.6)

0.467

  1. *Skin rash was strongly associated with the ASD-NSIP and i-NSIP-Ab + groups relative to the i-NSIP-Ab- group at the time of surgical lung biopsy or after re-classification.
  2. **Morning stiffness and Gastroesophageal reflux were associated with ASD-NSIP at the time of surgical lung biopsy. No differences among the three groups after re-classification at the time of follow-up.
  3. ASD = systemic autoimmune disease.